Abstract
Two patients with chronic myelogenous leukemia and new variant Philadelphia chromosome translocations are reported. In one case, a 41-year-old male, a 10;22 translocation was found in all bone marrow cells examined. Furthermore, the Y chromosome was missing in 90% of the analyzed metaphase cells. In the second patient, a 22-year-old male, all the marrow cells contained a complex rearrangement involving chromosomes No. 2, 9, and 22.
Original language | English |
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Pages (from-to) | 79-84 |
Number of pages | 6 |
Journal | Cancer Genetics and Cytogenetics |
Volume | 7 |
Issue number | 1 |
DOIs | |
State | Published - Sep 1982 |
Keywords
- Adult
- Chromosome Deletion
- Chromosomes, Human, 1-3/ultrastructure
- Chromosomes, Human, 21-22 and Y/ultrastructure
- Chromosomes, Human, 6-12 and X/ultrastructure
- Genetic Variation
- Humans
- Leukemia, Myeloid/genetics
- Male
- Translocation, Genetic
- Y Chromosome/ultrastructure