Uterine adenomyoma with lymphoid infiltration simulating lymphoma

Uterine leiomyoma with lymphoid infiltration is a rare disease that simulates malignant lymphoma with only nine cases reported to date. We describe the first case of uterine adenomyoma with lymphoid infiltration simulating lymphoma. The specimen resected from a 30-year-old Chinese woman was a well-defined firm nodule measuring 5 Ã- 5.5 Ã- 5.5 cm. The cut surface was similar to that of adenomyoma, which contained dark brown spots and a cyst. Microscopically, the tumor comprised smooth muscle cells intermixed with many lymphocytes. Many lymphoid follicles were present, just locating beside one side of thin-walled blood vessels and protruding into the vessels. Endometrial-type glands and stroma were visible in the tumor. We describe the first case of uterine adenomyoma with lymphoid infiltration simulating lymphoma.