Translational Research in Melanoma

Madhury Ray; Jeffrey M. Farma; Cary Hsu

doi:10.1016/j.soc.2013.06.009

Translational Research in Melanoma

Madhury Ray, Jeffrey M. Farma, Cary Hsu

University of California at Los Angeles

Research output: Contribution to journal › Review article › peer-review

Abstract

Recent breakthroughs in the fundamental understanding of the cellular and molecular basis of melanoma have culminated in new therapies with unquestionable efficacy. Immunotherapy and targeted therapy strategies have completely transformed the contemporary management of advanced melanoma. The translational research behind these developments is discussed, with an emphasis on immune checkpoint blockade and inhibition of the mitogen-activated protein kinase signaling pathway.

Original language	English
Pages (from-to)	785-804
Number of pages	20
Journal	Surgical Oncology Clinics of North America
Volume	22
Issue number	4
DOIs	https://doi.org/10.1016/j.soc.2013.06.009
State	Published - Oct 2013

Keywords

Immunotherapy
Melanoma
Targeted therapy
Translational research

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10.1016/j.soc.2013.06.009

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title = "Translational Research in Melanoma",

abstract = "Recent breakthroughs in the fundamental understanding of the cellular and molecular basis of melanoma have culminated in new therapies with unquestionable efficacy. Immunotherapy and targeted therapy strategies have completely transformed the contemporary management of advanced melanoma. The translational research behind these developments is discussed, with an emphasis on immune checkpoint blockade and inhibition of the mitogen-activated protein kinase signaling pathway.",

keywords = "Immunotherapy, Melanoma, Targeted therapy, Translational research",

author = "Madhury Ray and Farma, {Jeffrey M.} and Cary Hsu",

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Translational Research in Melanoma

Abstract

Keywords

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