Thymomas and thymic carcinomas

David S. Ettinger, Gregory J. Riely, Wallace Akerley, Hossein Borghaei, Andrew C. Chang, Richard T. Cheney, Lucian R. Chirieac, Thomas A. D'Amico, Todd L. Demmy, Ramaswamy Govindan, Frederic W. Grannis, Stefan C. Grant, Leora Horn, Thierry M. Jahan, Ritsuko Komaki, Feng Ming Kong, Mark G. Kris, Lee M. Krug, Rudy P. Lackner, Inga T. LennesBilly W. Loo, Renato Martins, Gregory A. Otterson, Jyoti D. Patel, Mary C. Pinder-Schenck, Katherine M. Pisters, Karen Reckamp, Eric Rohren, Theresa A. Shapiro, Scott J. Swanson, Kurt Tauer, Douglas E. Wood, Stephen C. Yang, Kristina Gregory, Miranda Hughes

Research output: Contribution to journalArticlepeer-review

70 Scopus citations

Abstract

Masses in the anterior mediastinum can be neoplasms (eg, thymomas, thymic carcinomas, or lung metastases) or nonneoplastic conditions (eg, intrathoracic goiter). Thymomas are the most common primary tumor in the anterior mediastinum, although they are rare. Thymic carcinomas are very rare. Thymomas and thymic carcinomas originate in the thymus. Although thymomas can spread locally, they are much less invasive than thymic carcinomas. Patients with thymomas have 5-year survival rates of approximately 78%. However, 5-year survival rates for thymic carcinomas are only approximately 40%. These guidelines outline the evaluation, treatment, and management of these mediastinal tumors.

Original languageEnglish
Pages (from-to)562-576
Number of pages15
JournalJournal of the National Comprehensive Cancer Network : JNCCN
Volume11
Issue number5
DOIs
StatePublished - 2013

Keywords

  • Humans
  • Thymoma/diagnosis
  • Thymus Neoplasms/diagnosis

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