The MLC response of patients with infectious mononucleosis to Epstein-Barr virus-transformed cells.

M. Wasik, A. Myc, H. Matej, L. Rudzka

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Abstract

Lymphocytes of 6 patients with infectious mononucleosis were found to be capable of responding in mixed lymphocyte culture (MLC) to Epstein-Barr virus (EBV)--transformed lymphoblastoid cell lines and Raji cells, whereas their response to PWM-induced blasts and non-T cells was significantly depressed. This means that despite the suppression of cellular reactivity, observed in infectious mononucleosis, the specific response to EBV-infected cells remains unaffected.

Original languageEnglish
Pages (from-to)871-878
Number of pages8
JournalArchivum Immunologiae et Therapiae Experimentalis
Volume31
Issue number6
StatePublished - 1983

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