The forkhead transcription factors play important roles invascular pathology and immunology

Xiao Feng Yang; Pu Fang; Shu Meng; Michael Jan; Xinyu Xiong; Ying Yin; Hong Wang

doi:10.1007/978-1-4419-1599-3_7

The forkhead transcription factors play important roles invascular pathology and immunology

Xiao Feng Yang
, Pu Fang
, Shu Meng
, Michael Jan
, Xinyu Xiong
, Ying Yin
, Hong Wang

Nuclear Dynamics and Cancer (NDC)

Temple University

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

11 Scopus citations

Abstract

Transcription factor families are a small number of upstream master genes in "higher hierarchy" that control the expression of a large number of downstream genes. These transcription factorshavebeen found to integrate the signalingpathways underlyingthe pathogenesis of cardiovascular diseases with or without autoimmuneinflammatorymechanisms. In this chapter,weorganizeour analysisof recentprogressin characterization offorkhead (FOX) transcriptionfactorfamily members in vascular pathologyandimmuneregulationinto the followingsections: (1) Introduction of the FOXtranscriptionfactorsuperfamily; (2)FOXtranscription factorsand endothelialcellpathology; (3) FOXtranscription factorsandvascular smooth muscle cells;and (4)FOXtranscription factors, inflammation andimmunesystem.Advances in theseareas suggest that the FOX transcriptionfactor familyisimportant in regulatingvascular development and the pathogenesis of autoimmuneinflammatorycardiovascular diseases.

Original language	English
Title of host publication	Forkhead Transcription Factors
Subtitle of host publication	Vital Elements in Biology and Medicine
Publisher	Springer New York
Pages	90-105
Number of pages	16
Volume	665
ISBN (Print)	9781441915986
DOIs	https://doi.org/10.1007/978-1-4419-1599-3_7
State	Published - 2009

Publication series

Name	Advances in Experimental Medicine and Biology
Volume	665
ISSN (Print)	0065-2598

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Animals
Endothelium, Vascular/pathology
Forkhead Transcription Factors/physiology
Humans
Immune System/physiology
Inflammation/metabolism
Muscle, Smooth, Vascular/pathology

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10.1007/978-1-4419-1599-3_7

Cite this

Yang, X. F., Fang, P., Meng, S., Jan, M., Xiong, X., Yin, Y., & Wang, H. (2009). The forkhead transcription factors play important roles invascular pathology and immunology. In Forkhead Transcription Factors: Vital Elements in Biology and Medicine (Vol. 665, pp. 90-105). (Advances in Experimental Medicine and Biology; Vol. 665). Springer New York. https://doi.org/10.1007/978-1-4419-1599-3_7

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Yang, XF, Fang, P, Meng, S, Jan, M, Xiong, X, Yin, Y & Wang, H 2009, The forkhead transcription factors play important roles invascular pathology and immunology. in Forkhead Transcription Factors: Vital Elements in Biology and Medicine. vol. 665, Advances in Experimental Medicine and Biology, vol. 665, Springer New York, pp. 90-105. https://doi.org/10.1007/978-1-4419-1599-3_7

The forkhead transcription factors play important roles invascular pathology and immunology. / Yang, Xiao Feng; Fang, Pu; Meng, Shu et al.
Forkhead Transcription Factors: Vital Elements in Biology and Medicine. Vol. 665 Springer New York, 2009. p. 90-105 (Advances in Experimental Medicine and Biology; Vol. 665).

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

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AU - Yang, Xiao Feng

AU - Fang, Pu

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AU - Jan, Michael

AU - Xiong, Xinyu

AU - Yin, Ying

AU - Wang, Hong

PY - 2009

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KW - Endothelium, Vascular/pathology

KW - Forkhead Transcription Factors/physiology

KW - Humans

KW - Immune System/physiology

KW - Inflammation/metabolism

KW - Muscle, Smooth, Vascular/pathology

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DO - 10.1007/978-1-4419-1599-3_7

M3 - Chapter

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AN - SCOPUS:77952500002

SN - 9781441915986

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T3 - Advances in Experimental Medicine and Biology

SP - 90

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BT - Forkhead Transcription Factors

PB - Springer New York

ER -

The forkhead transcription factors play important roles invascular pathology and immunology

Abstract

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UN SDGs

Keywords

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