@inbook{5b53934026a841b7bb284174d72adce0,
title = "The forkhead transcription factors play important roles invascular pathology and immunology",
abstract = "Transcription factor families are a small number of upstream master genes in {"}higher hierarchy{"} that control the expression of a large number of downstream genes. These transcription factorshavebeen found to integrate the signalingpathways underlyingthe pathogenesis of cardiovascular diseases with or without autoimmuneinflammatorymechanisms. In this chapter,weorganizeour analysisof recentprogressin characterization offorkhead (FOX) transcriptionfactorfamily members in vascular pathologyandimmuneregulationinto the followingsections: (1) Introduction of the FOXtranscriptionfactorsuperfamily; (2)FOXtranscription factorsand endothelialcellpathology; (3) FOXtranscription factorsandvascular smooth muscle cells;and (4)FOXtranscription factors, inflammation andimmunesystem.Advances in theseareas suggest that the FOX transcriptionfactor familyisimportant in regulatingvascular development and the pathogenesis of autoimmuneinflammatorycardiovascular diseases.",
keywords = "Animals, Endothelium, Vascular/pathology, Forkhead Transcription Factors/physiology, Humans, Immune System/physiology, Inflammation/metabolism, Muscle, Smooth, Vascular/pathology",
author = "Yang, {Xiao Feng} and Pu Fang and Shu Meng and Michael Jan and Xinyu Xiong and Ying Yin and Hong Wang",
year = "2009",
doi = "10.1007/978-1-4419-1599-3_7",
language = "English",
isbn = "9781441915986",
volume = "665",
series = "Advances in Experimental Medicine and Biology",
publisher = "Springer New York",
pages = "90--105",
booktitle = "Forkhead Transcription Factors",
address = "United States",
}
