The Few yet Fabp4ulous Pancreatic Stellate Cells Give Rise to Protumoral CAFs

Edna Cukierman

doi:10.1158/2159-8290.CD-21-1501

The Few yet Fab_p4ulous Pancreatic Stellate Cells Give Rise to Protumoral CAFs

Research output: Contribution to journal › Article › peer-review

Abstract

Cancer-associated fibroblast (CAF) pro- and anti-pancreatic cancer functional dichotomy has been at the center of numerous studies. In this issue of Cancer Discovery, Helms and colleagues demonstrate that although pancreatic stellate cell-derived CAFs constitute a desmoplastic cell minority, these cells play a protumorigenic role via microenvironmental mechanomodulation. See related article by Helms et al., p. 484.

Original language	English
Pages (from-to)	296-298
Number of pages	3
Journal	Cancer Discovery
Volume	12
Issue number	2
DOIs	https://doi.org/10.1158/2159-8290.CD-21-1501
State	Published - Feb 1 2022

Keywords

Cancer-Associated Fibroblasts
Carcinoma, Pancreatic Ductal
Humans
Pancreatic Neoplasms
Pancreatic Stellate Cells

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10.1158/2159-8290.CD-21-1501

Cite this

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abstract = "Cancer-associated fibroblast (CAF) pro- and anti-pancreatic cancer functional dichotomy has been at the center of numerous studies. In this issue of Cancer Discovery, Helms and colleagues demonstrate that although pancreatic stellate cell-derived CAFs constitute a desmoplastic cell minority, these cells play a protumorigenic role via microenvironmental mechanomodulation. See related article by Helms et al., p. 484. ",

keywords = "Cancer-Associated Fibroblasts, Carcinoma, Pancreatic Ductal, Humans, Pancreatic Neoplasms, Pancreatic Stellate Cells",

author = "Edna Cukierman",

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The Few yet Fab_p4ulous Pancreatic Stellate Cells Give Rise to Protumoral CAFs

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The Few yet Fabp4ulous Pancreatic Stellate Cells Give Rise to Protumoral CAFs

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The Few yet Fab_p4ulous Pancreatic Stellate Cells Give Rise to Protumoral CAFs