The Expression of IL-21 Is Promoted by MEKK4 in Malignant T Cells and Associated with Increased Progression Risk in Cutaneous T-Cell Lymphoma

Simon Fredholm, Ivan V. Litvinov, Nigel P. Mongan, Sarah Schiele, Andreas Willerslev-Olsen, David Leander Petersen, Thorbjørn Krejsgaard, Nina Sibbesen, Claudia Nastasi, Charlotte M. Bonefeld, Jenny L. Persson, Per Thor Straten, Mads Hald Andersen, Sergei B. Koralov, Mariusz M. Wasik, Carsten Geisler, Denis Sasseville, Anders Woetmann, Niels Ødum

Research output: Contribution to journalArticlepeer-review

5 Scopus citations
Original languageEnglish
Pages (from-to)866-869
Number of pages4
JournalJournal of Investigative Dermatology
Volume136
Issue number4
DOIs
StatePublished - 2016

Keywords

  • Disease Progression
  • Gene Expression Regulation, Neoplastic
  • Humans
  • Inflammation
  • Interleukins/genetics
  • Lymphoma, T-Cell/metabolism
  • MAP Kinase Kinase Kinase 4/metabolism
  • MAP Kinase Signaling System
  • Phosphorylation
  • RNA, Small Interfering/metabolism
  • STAT3 Transcription Factor/metabolism
  • Signal Transduction
  • Skin Neoplasms/metabolism
  • T-Lymphocytes/metabolism

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