TY - JOUR
T1 - Sonography of diffuse benign liver disease
T2 - Accuracy of pattern recognition and grading
AU - Needleman, L.
AU - Kurtz, A. B.
AU - Rifkin, M. D.
AU - Cooper, H. S.
AU - Pasto, M. E.
AU - Goldberg, B. B.
PY - 1986
Y1 - 1986
N2 - Sonograms of 110 patients were compared to recently performed liver biopsies for evaluation of the accuracy of sonography in predicting the type (pattern) of pathology and its grade of severity (mild, moderate, or severe) in a wide variety of diffuse liver processes. There are two distinct, abnormal sonographic patterns: (1) the fatty-fibrotic pattern seen primarily with cirrhosis, chronic hepatitis, and/or fatty infiltration, and (2) the centrilobular pattern seen primarily with acute hepatitis. Sonography was 88% accurate in assigning the correct pattern to the corresponding pathology (sensitivity 89%, specificity 86%, p < 0.001). The degree of accuracy was dependent on the grade of pathologic severity, with mild disease offering the greatest difficulty; moderate and severe diseases were accurately detected and placed in the correct pattern in all cases. Sonographic grading of the severity of the disease was far less precise (63% overall). This study showed that sonography can distinguish between two abnormal sonographic patterns of diffuse benign liver disease as well as between normal and abnormal patterns.
AB - Sonograms of 110 patients were compared to recently performed liver biopsies for evaluation of the accuracy of sonography in predicting the type (pattern) of pathology and its grade of severity (mild, moderate, or severe) in a wide variety of diffuse liver processes. There are two distinct, abnormal sonographic patterns: (1) the fatty-fibrotic pattern seen primarily with cirrhosis, chronic hepatitis, and/or fatty infiltration, and (2) the centrilobular pattern seen primarily with acute hepatitis. Sonography was 88% accurate in assigning the correct pattern to the corresponding pathology (sensitivity 89%, specificity 86%, p < 0.001). The degree of accuracy was dependent on the grade of pathologic severity, with mild disease offering the greatest difficulty; moderate and severe diseases were accurately detected and placed in the correct pattern in all cases. Sonographic grading of the severity of the disease was far less precise (63% overall). This study showed that sonography can distinguish between two abnormal sonographic patterns of diffuse benign liver disease as well as between normal and abnormal patterns.
KW - Biopsy
KW - Diagnostic Errors
KW - Fatty Liver/pathology
KW - Hepatitis/pathology
KW - Humans
KW - Liver Diseases/pathology
KW - Pattern Recognition, Automated
KW - Retrospective Studies
KW - Ultrasonography
UR - http://www.scopus.com/inward/record.url?scp=0022610211&partnerID=8YFLogxK
UR - https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=purepublist2023&SrcAuth=WosAPI&KeyUT=WOS:A1986C009100017&DestLinkType=FullRecord&DestApp=WOS
U2 - 10.2214/ajr.146.5.1011
DO - 10.2214/ajr.146.5.1011
M3 - Article
C2 - 3515875
SN - 0361-803X
VL - 146
SP - 1011
EP - 1015
JO - American Journal of Roentgenology
JF - American Journal of Roentgenology
IS - 5
ER -