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Small bowel adenocarcinoma, version 1.2020

  • Al B. Benson
  • , Alan P. Venook
  • , Mahmoud M. Al-Hawary
  • , Mustafa A. Arain
  • , Yi Jen Chen
  • , Kristen K. Ciombor
  • , Stacey A. Cohen
  • , Harry S. Cooper
  • , Dustin A. Deming
  • , Ignacio Garrido-Laguna
  • , Jean L. Grem
  • , Sarah E. Hoffe
  • , Joleen Hubbard
  • , Steven Hunt
  • , Ahmed Kamel
  • , Natalie Kirilcuk
  • , Smitha Krishnamurthi
  • , Wells A. Messersmith
  • , Jeffrey Meyerhardt
  • , Eric D. Miller
  • Mary F. Mulcahy, Nurkin, Md, Ms Steven Nurkin, Md, Ms, Michael J. Overman, Aparna Parikh, Hitendra Patel, Katrina S. Pedersen, Leonard B. Saltz, Charles Schneider, David Shibata, John M. Skibber, Constantinos T. Sofocleous, Elena M. Stoffel, Eden Stotsky-Himelfarb, Christopher G. Willett, Alyse Johnson-Chilla, Kristina M. Gregory, Lisa A. Gurski
  • Northwestern University
  • University of California at San Francisco
  • University of Michigan, Ann Arbor
  • City of Hope National Medical Center
  • Vanderbilt University
  • Seattle Cancer Care Alliance
  • University of Wisconsin-Madison
  • University of Utah
  • University of Nebraska Medical Center
  • University of South Florida
  • Mayo Clinic
  • Washington University St. Louis
  • University of Alabama at Birmingham
  • Stanford University
  • Case Western Reserve University
  • University of Colorado Cancer Center
  • Dana-Farber/Brigham and Women's Cancer Center
  • Ohio State University
  • Roswell Park Comprehensive Cancer Center
  • University of Texas MD Anderson Cancer Center
  • Massachusetts General Hospital Cancer Center
  • University of California at San Diego
  • Memorial Sloan-Kettering Cancer Center
  • University of Pennsylvania
  • University of Tennessee Health Science Center
  • Johns Hopkins University
  • Duke University
  • National Comprehensive Cancer Network

Research output: Contribution to journal › Review article › peer-review

164 Scopus citations

Abstract

Small bowel adenocarcinoma (SBA) is a rare malignancy of the gastrointestinal tract that has increased in incidence across recent years. Often diagnosed at an advanced stage, outcomes for SBA are worse on average than for other related malignancies, including colorectal cancer. Due to the rarity of this disease, few studies have been done to direct optimal treatment, although recent data have shown that SBA responds to treatment differently than colorectal cancer, necessitating a separate approach to treatment. The NCCN Guidelines for Small Bowel Adenocarcinoma were created to establish an evidence-based standard of care for patients with SBA. These guidelines provide recommendations on the workup of suspected SBA, primary treatment options, adjuvant treatment, surveillance, and systemic therapy for metastatic disease. Additionally, principles of imaging and endoscopy, pathologic review, surgery, radiation therapy, and survivorship are described.

Original languageEnglish
Pages (from-to)1109-1133
Number of pages25
JournalJournal of the National Comprehensive Cancer Network : JNCCN
Volume17
Issue number9
DOIs
StatePublished - 2019

Keywords

  • Adenocarcinoma/diagnosis
  • Combined Modality Therapy
  • Diagnosis, Differential
  • Humans
  • Intestinal Neoplasms/diagnosis
  • Intestine, Small/pathology
  • Neoplasm Staging
  • Practice Guidelines as Topic
  • Risk Factors
  • Survivorship
  • Treatment Outcome
  • Watchful Waiting

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