TY - JOUR
T1 - Resting energy expenditure of patients with gynecologic malignancies
AU - Dickerson, Roland N.
AU - White, Kimberly G.
AU - Curcillo, Paul G.
AU - King, Stephanie A.
AU - Mullen, James L.
PY - 1995/9
Y1 - 1995/9
N2 - OBJECTIVE: To evaluate resting energy expenditure compared to predicted energy expenditure in patients with cervical or ovarian carcinoma who require specialized nutritional support.DESIGN: Women with biopsy-proven cervical or ovarian carcinoma referred to the Nutrition Support Service were studied. Resting energy expenditure was measured by indirect calorimetry and compared to predicted energy expenditure (PEE) as determined by the Harris-Benedict equation for females.RESULTS: Sixty one patients were studied. Patients with ovarian cancer (n = 31) had a significantly higher measured resting energy expenditure (% PEE) than patients with cervical cancer (109 +/- 18% vs. 98 +/- 16%, p < 0.02, respectively). This difference in measured resting energy expenditure between groups could not be explained by differences in the extent of disease, nutritional status, body temperature, or nutrient intake between groups. A greater proportion of patients with ovarian cancer were hypermetabolic (> 110% of predicted) in comparison to patients with cervical cancer (55% vs. 13%, p < 0.01, respectively). Measured resting energy expenditure varied between 53% and 157% of predicted for the entire population.CONCLUSION: Ovarian cancer patients are more hypermetabolic than cervical cancer patients. The Harris-Benedict equation for females is a unreliable estimate of caloric expenditure in patients with cervical or ovarian cancer receiving specialized nutritional support.
AB - OBJECTIVE: To evaluate resting energy expenditure compared to predicted energy expenditure in patients with cervical or ovarian carcinoma who require specialized nutritional support.DESIGN: Women with biopsy-proven cervical or ovarian carcinoma referred to the Nutrition Support Service were studied. Resting energy expenditure was measured by indirect calorimetry and compared to predicted energy expenditure (PEE) as determined by the Harris-Benedict equation for females.RESULTS: Sixty one patients were studied. Patients with ovarian cancer (n = 31) had a significantly higher measured resting energy expenditure (% PEE) than patients with cervical cancer (109 +/- 18% vs. 98 +/- 16%, p < 0.02, respectively). This difference in measured resting energy expenditure between groups could not be explained by differences in the extent of disease, nutritional status, body temperature, or nutrient intake between groups. A greater proportion of patients with ovarian cancer were hypermetabolic (> 110% of predicted) in comparison to patients with cervical cancer (55% vs. 13%, p < 0.01, respectively). Measured resting energy expenditure varied between 53% and 157% of predicted for the entire population.CONCLUSION: Ovarian cancer patients are more hypermetabolic than cervical cancer patients. The Harris-Benedict equation for females is a unreliable estimate of caloric expenditure in patients with cervical or ovarian cancer receiving specialized nutritional support.
KW - Adult
KW - Aged
KW - Basal Metabolism
KW - Calorimetry, Indirect
KW - Female
KW - Humans
KW - Middle Aged
KW - Nutrition Assessment
KW - Nutritional Support
KW - Ovarian Neoplasms/metabolism
KW - Predictive Value of Tests
KW - Reproducibility of Results
KW - Rest
KW - Uterine Cervical Neoplasms/metabolism
UR - http://www.scopus.com/inward/record.url?scp=0029096417&partnerID=8YFLogxK
UR - https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=purepublist2023&SrcAuth=WosAPI&KeyUT=WOS:A1995RX30700008&DestLinkType=FullRecord&DestApp=WOS
U2 - 10.1080/07315724.1995.10718535
DO - 10.1080/07315724.1995.10718535
M3 - Article
C2 - 8522723
SN - 0731-5724
VL - 14
SP - 448
EP - 454
JO - Journal of the American College of Nutrition
JF - Journal of the American College of Nutrition
IS - 5
ER -
