Resolution of a Debilitating Paraneoplastic Parkinson-like Neurological Syndrome Following Tyrosine Inhibitor Therapy and Consolidative Nephrectomy in a Patient with Advanced Clear Cell Renal Cell Carcinoma

Naveed Ali; Alexander Kutikov; Daniel M. Geynisman

doi:10.1016/j.eucr.2017.05.007

Resolution of a Debilitating Paraneoplastic Parkinson-like Neurological Syndrome Following Tyrosine Inhibitor Therapy and Consolidative Nephrectomy in a Patient with Advanced Clear Cell Renal Cell Carcinoma

Naveed Ali, Alexander Kutikov, Daniel M. Geynisman

Fox Chase Cancer Center

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Abstract

Paraneoplastic syndromes are commonly encountered in renal cell carcinoma, but neurological manifestations are rare. Herein we report a case of a patient with locally advanced renal cell carcinoma who presented with Parkinson-like symptoms which prohibited surgery due to poor performance status. However, a significant improvement was noted after tyrosine kinase inhibitor therapy, allowing the patient to proceed to curative surgery.

Original language	English
Pages (from-to)	18-20
Number of pages	3
Journal	Urology Case Reports
Volume	14
DOIs	https://doi.org/10.1016/j.eucr.2017.05.007
State	Published - Sep 2017

Keywords

Paraneoplastic syndrome
Renal cell carcinoma
Tyrosine kinase inhibitor therapy

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10.1016/j.eucr.2017.05.007

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abstract = "Paraneoplastic syndromes are commonly encountered in renal cell carcinoma, but neurological manifestations are rare. Herein we report a case of a patient with locally advanced renal cell carcinoma who presented with Parkinson-like symptoms which prohibited surgery due to poor performance status. However, a significant improvement was noted after tyrosine kinase inhibitor therapy, allowing the patient to proceed to curative surgery.",

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Resolution of a Debilitating Paraneoplastic Parkinson-like Neurological Syndrome Following Tyrosine Inhibitor Therapy and Consolidative Nephrectomy in a Patient with Advanced Clear Cell Renal Cell Carcinoma. / Ali, Naveed; Kutikov, Alexander ; Geynisman, Daniel M.
In: Urology Case Reports, Vol. 14, 09.2017, p. 18-20.

Research output: Contribution to journal › Article › peer-review

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