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Rectal cancer, version 6.2020: Featured updates to the NCCN guidelines

  • Al B. Benson
  • , Alan P. Venook
  • , Mahmoud M. Al-Hawary
  • , Mustafa A. Arain
  • , Yi Jen Chen
  • , Kristen K. Ciombor
  • , Stacey Cohen
  • , Harry S. Cooper
  • , Dustin Deming
  • , Ignacio Garrido-Laguna
  • , Jean L. Grem
  • , Andrew Gunn
  • , Sarah Hoffe
  • , Joleen Hubbard
  • , Steven Hunt
  • , Natalie Kirilcuk
  • , Smitha Krishnamurthi
  • , Wells A. Messersmith
  • , Jeffrey Meyerhardt
  • , Eric D. Miller
  • Mary F. Mulcahy, Steven Nurkin, Michael J. Overman, Aparna Parikh, Hitendra Patel, Katrina Pedersen, Leonard Saltz, Charles Schneider, David Shibata, John M. Skibber, Constantinos T. Sofocleous, Elena M. Stoffel, Eden Stotsky-Himelfarb, Christopher G. Willett, Alyse Johnson-Chilla, Lisa A. Gurski
  • Northwestern University
  • City of Hope National Medical Center
  • University of California at San Francisco
  • University of Michigan, Ann Arbor
  • Vanderbilt University
  • Fred Hutchinson Cancer Research Center
  • University of Wisconsin-Madison
  • University of Utah
  • University of Nebraska Medical Center
  • O'Neal Comprehensive Cancer Center at the University of Alabama at Birmingham
  • University of South Florida
  • Mayo Clinic
  • Washington University St. Louis
  • Stanford University
  • Cleveland Clinic Foundation
  • University of Colorado Cancer Center
  • Dana-Farber/Brigham and Women's Cancer Center
  • Ohio State University
  • Roswell Park Comprehensive Cancer Center
  • University of Texas MD Anderson Cancer Center
  • Massachusetts General Hospital Cancer Center
  • University of California at San Diego
  • Memorial Sloan-Kettering Cancer Center
  • University of Pennsylvania
  • University of Tennessee Health Science Center
  • Johns Hopkins University
  • Duke University
  • National Comprehensive Cancer Network

Research output: Contribution to journal › Review article › peer-review

436 Scopus citations

Abstract

The NCCN Guidelines for Rectal Cancer provide recommendations for the diagnosis, evaluation, treatment, and follow-up of patients with rectal cancer. These NCCN Guidelines Insights summarize the panel discussion behind recent important updates to the guidelines. These updates include clarifying the definition of rectum and differentiating the rectumfromthe sigmoid colon; the total neoadjuvant therapy approach for localized rectal cancer; and biomarker-targeted therapy for metastatic colorectal cancer, with a focus on new treatment options for patients with BRAF V600E- or HER2 amplification- positive disease.

Original languageEnglish
Pages (from-to)807-815
Number of pages9
JournalJournal of the National Comprehensive Cancer Network : JNCCN
Volume18
Issue number7
DOIs
StatePublished - Jul 2020

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

Keywords

  • Colonic Neoplasms/diagnosis
  • Humans
  • Neoadjuvant Therapy
  • Practice Guidelines as Topic
  • Rectal Neoplasms/diagnosis

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