Recent advances in immunotherapy and monoclonal antibody treatment of cancer

Jonathan D. Cheng, Paula T. Rieger, Margaret von Mehren, Gregory P. Adams, Louis M. Weiner

Research output: Contribution to journalArticlepeer-review

17 Scopus citations

Abstract

OBJECTIVES: To review the immune response and tumor immunology, and to provide an update on the success and obstacles to targeted therapy using monoclonal antibodies and antibody conjugates. DATA SOURCES: Research articles and textbooks. CONCLUSIONS: Ongoing studies are exploiting the targeting properties of the immune system to improve anticancer therapy. Both monoclonal antibodies and immunoconjugates have shown promise in treatment of specific diseases. IMPLICATIONS FOR NURSING PRACTICE: The rapid growth of molecular techniques has allowed for the development of new anticancer therapies. Since nurses are intimately involved in the delivery of such therapy as well as in educating patients regarding risks and benefits, they must be knowledgeable.

Original languageEnglish
Pages (from-to)2-12
Number of pages11
JournalSeminars in Oncology Nursing
Volume16
Issue number4
DOIs
StatePublished - Nov 2000

Keywords

  • Antibodies, Monoclonal/therapeutic use
  • Humans
  • Immunotherapy
  • Neoplasm Metastasis
  • Neoplasms/nursing
  • Oncology Nursing

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