Abstract
The term "pyroptosis" was originally introduced to describe a particular form of cell death in macrophages, which is induced by bacterial infection, is accompanied by caspase-1 activation and hence leads to the release of pyrogenic interleukins; however, it is still controversial whether pyroptosis - which can also be triggered by nonbacterial pathological stimuli - truly represents a cell death modality on its own or whether it constitutes a special case of apoptosis or necrosis.
Original language | English |
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Pages (from-to) | 627-630 |
Number of pages | 4 |
Journal | European Journal of Immunology |
Volume | 40 |
Issue number | 3 |
DOIs | |
State | Published - Mar 2010 |
Externally published | Yes |
Keywords
- Apoptosis
- Inflammation
- Macrophages