Pure red cell aplasia in B-cell lymphoproliferative disorder treated with rituximab: Report of two cases and review of the literature

  • Kalyani Narra
  • , Hossein Borghaei
  • , Tahseen Al-Saleem
  • , Martin Höglund
  • , Mitchell R. Smith

Research output: Contribution to journalArticlepeer-review

38 Scopus citations

Abstract

Pure red cell aplasia (PRCA) is an unusual cause of anemia in patients with chronic lymphoproliferative disorders. Here, we present two cases of PRCA, one associated with chronic lymphocytic leukemia (CLL) and the other with splenic marginal zone lymphoma, in which the PRCA responded dramatically to treatment with rituximab. We then review the literature on PRCA in lymphoma and response to rituximab. PRCA associated with CLL or lymphoma may be another indication for rituximab therapy.

Original languageEnglish
Pages (from-to)109-114
Number of pages6
JournalLeukemia Research
Volume30
Issue number1
DOIs
StatePublished - Jan 2006

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

Keywords

  • Antibodies, Monoclonal, Murine-Derived
  • Antibodies, Monoclonal/administration & dosage
  • Antineoplastic Agents/administration & dosage
  • Female
  • Humans
  • Leukemia, Lymphocytic, Chronic, B-Cell/complications
  • Lymphoma/complications
  • Middle Aged
  • Red-Cell Aplasia, Pure/complications
  • Rituximab

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