Pulmonary Wegener's granulomatosis

A. S. Patchefsky, H. L. Israel

Research output: Contribution to journalArticlepeer-review

5 Scopus citations

Abstract

The clinical course, radiographic features and pathology of 18 cases of Wegener's granulomatosis with pulmonary involvement are presented. Glomerulitis and generalized vasculitis were not among the features of this series. Nodular pulmonary densities characterized the chest radiographs. Five cases showed improvement in one lung with progression in the other, thus differentiating the disease from neoplasia. Vasculitis, rarely with fibrinoid necrosis, characterized the pathology. Cytotoxic drugs caused sustained clinical improvement in 6 patients and appear to be the treatment of choice.

Original languageEnglish
Pages (from-to)249-258
Number of pages10
JournalAnnals of Clinical and Laboratory Science
Volume3
Issue number4
StatePublished - 1973

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