TY - JOUR
T1 - Prostate irradiation as an alternative to the conventional management of benign prostatic hypertrophy
AU - Costleigh, Brian
AU - Keit, Joan
AU - Miyamoto, Curtis
AU - Mieszkalski, Glenn
AU - Brady, Luther W.
AU - Micaily, Bizhan
PY - 1995
Y1 - 1995
N2 - To help determine the efficacy of radiation therapy (RT) as an alternative to conventional treatment of benign prostatic hypertrophy (BPH), seven patients were treated at Hahnemann University Hospital (Philadelphia, PA), between November 1981 and May 1988, with megavoltage RT for BPH. Indications for treatment included severely symptomatic disease while having medical contraindications to, or refusal of conventional treatments. Doses ranged from 2,000 to 2,400 cGy, using 300–400 cGy fractions twice per week for 2.5–3 weeks. Radiation was delivered using 6 MV photons. All patients experienced good relief of both irritative and obstructive symptoms. Six of seven patients remained free of recurrent symptoms. There were no short‐ or long‐term complications. These preliminary data suggest that there may be a future role for RT in the treatment of BPH in the medically inoperable patient. However, further study is needed before this can be seriously considered a standard treatment alternative. © 1995 Wiley‐Liss, Inc.
AB - To help determine the efficacy of radiation therapy (RT) as an alternative to conventional treatment of benign prostatic hypertrophy (BPH), seven patients were treated at Hahnemann University Hospital (Philadelphia, PA), between November 1981 and May 1988, with megavoltage RT for BPH. Indications for treatment included severely symptomatic disease while having medical contraindications to, or refusal of conventional treatments. Doses ranged from 2,000 to 2,400 cGy, using 300–400 cGy fractions twice per week for 2.5–3 weeks. Radiation was delivered using 6 MV photons. All patients experienced good relief of both irritative and obstructive symptoms. Six of seven patients remained free of recurrent symptoms. There were no short‐ or long‐term complications. These preliminary data suggest that there may be a future role for RT in the treatment of BPH in the medically inoperable patient. However, further study is needed before this can be seriously considered a standard treatment alternative. © 1995 Wiley‐Liss, Inc.
KW - benign prostatic hypertrophy
KW - prostatectomy
KW - radiotherapy
KW - therapy
UR - http://www.scopus.com/inward/record.url?scp=84982758334&partnerID=8YFLogxK
U2 - 10.1002/roi.2970030206
DO - 10.1002/roi.2970030206
M3 - Article
AN - SCOPUS:84982758334
SN - 1065-7541
VL - 3
SP - 72
EP - 76
JO - Radiation Oncology Investigations
JF - Radiation Oncology Investigations
IS - 2
ER -