Prostate cancer, version 1.2014: Featured updates to the NCCN Guidelines

James L. Mohler, Philip W. Kantoff, Andrew J. Armstrong, Robert R. Bahnson, Michael Cohen, Anthony Victor D'Amico, James A. Eastham, Charles A. Enke, Thomas A. Farrington, Celestia S. Higano, Eric Mark Horwitz, Mark H. Kawachi, Michael Kuettel, Richard J. Lee, Gary R. MacVicar, Arnold W. Malcolm, David Miller, Elizabeth R. Plimack, Julio M. Pow-Sang, Sylvia RicheyMack Roach, Eric Rohren, Stan Rosenfeld, Eric J. Small, Sandy Srinivas, Cy Stein, Seth A. Strope, Jonathan Tward, Patrick C. Walsh, Dorothy A. Shead, Maria Ho

Research output: Contribution to journalReview articlepeer-review

85 Scopus citations

Abstract

The NCCN Guidelines for Prostate Cancer provide multidisciplinary recommendations on the clinical management of patients with prostate cancer. This report highlights notable recent updates. Radium-223 dichloride is a first-in-class radiopharmaceutical that recently received approval for the treatment of patients with symptomatic bone metastases and no known visceral disease. It received a category 1 recommendation as both a first-line and second-line option. The NCCN Prostate Cancer Panel also revised recommendations on the choice of intermittent or continuous androgen deprivation therapy based on recent phase III clinical data comparing the 2 strategies in the nonmetastatic and metastatic settings.

Original languageEnglish
Pages (from-to)1471-1479
Number of pages9
JournalJournal of the National Comprehensive Cancer Network : JNCCN
Volume11
Issue number12
DOIs
StatePublished - Dec 1 2013

Keywords

  • Bone Neoplasms/secondary
  • Humans
  • Male
  • Neoplasm Staging
  • Prostatic Neoplasms/diagnosis
  • Radioisotopes/therapeutic use
  • Radium/therapeutic use
  • Recurrence

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