Promising new agents in the treatment of non-small cell lung cancer

Martin J. Edelman; David R. Gandara

doi:10.1007/s002800050402

Promising new agents in the treatment of non-small cell lung cancer

Martin J. Edelman, David R. Gandara

VA Medical Center

Research output: Contribution to journal › Review article › peer-review

45 Scopus citations

Abstract

A number of new drugs and drug classes have recently become available for clinical testing which demonstrate significant antitumor activity in non-small cell lung cancer. The preclinical rationale, mechanism of action, toxicity profile and results of early trials of paclitaxel, docetaxel, edatrexate, CPT-11, topotecan, vinorelbine and gemcitabine in non-small cell lung cancer are reviewed.

Original language	English
Pages (from-to)	385-393
Number of pages	9
Journal	Cancer Chemotherapy and Pharmacology
Volume	37
Issue number	5
DOIs	https://doi.org/10.1007/s002800050402
State	Published - 1996

Keywords

CPT-11
Docetaxel
Gemcitabine
Lung cancer
Topotecan
Vinorelbine
jPaclitaxel

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1007/s002800050402

Cite this

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abstract = "A number of new drugs and drug classes have recently become available for clinical testing which demonstrate significant antitumor activity in non-small cell lung cancer. The preclinical rationale, mechanism of action, toxicity profile and results of early trials of paclitaxel, docetaxel, edatrexate, CPT-11, topotecan, vinorelbine and gemcitabine in non-small cell lung cancer are reviewed.",

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AU - Gandara, David R.

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AB - A number of new drugs and drug classes have recently become available for clinical testing which demonstrate significant antitumor activity in non-small cell lung cancer. The preclinical rationale, mechanism of action, toxicity profile and results of early trials of paclitaxel, docetaxel, edatrexate, CPT-11, topotecan, vinorelbine and gemcitabine in non-small cell lung cancer are reviewed.

KW - CPT-11

KW - Docetaxel

KW - Gemcitabine

KW - Lung cancer

KW - Topotecan

KW - Vinorelbine

KW - jPaclitaxel

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DO - 10.1007/s002800050402

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JO - Cancer Chemotherapy and Pharmacology

JF - Cancer Chemotherapy and Pharmacology

IS - 5

ER -

Promising new agents in the treatment of non-small cell lung cancer

Abstract

Keywords

UN SDGs

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