Prognostic value of atypical B cells in breast cancer

Esmeralda García-Torralba; Lorenzo Galluzzi; Aitziber Buqué

doi:10.1016/j.trecan.2024.09.009

Prognostic value of atypical B cells in breast cancer

Esmeralda García-Torralba, Lorenzo Galluzzi, Aitziber Buqué

Cancer Signaling and Microenvironment (CSM)

Research output: Contribution to journal › Article › peer-review

Abstract

The impact of tumor-infiltrating B cells on breast cancer (BRCA) outcomes remains poorly understood. Recent findings from Yang et al. identify an atypical, clonally expanded population of activated Fc receptor-like 4 (FCRL4)⁺ B cells that is associated with improved overall survival in patients affected by various tumor types, including BRCA.

Original language	English
Pages (from-to)	990-991
Number of pages	2
Journal	Trends in Cancer
Volume	10
Issue number	11
DOIs	https://doi.org/10.1016/j.trecan.2024.09.009
State	Published - Nov 2024

Keywords

ABCs
CD8 cytotoxic T lymphocytes
TNBC
antigen presentation
germinal center
tertiary lymphoid structures
Lymphocytes, Tumor-Infiltrating/immunology
B-Lymphocytes/immunology
Prognosis
Humans
Breast Neoplasms/immunology
Female

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1016/j.trecan.2024.09.009

Cite this

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title = "Prognostic value of atypical B cells in breast cancer",

abstract = "The impact of tumor-infiltrating B cells on breast cancer (BRCA) outcomes remains poorly understood. Recent findings from Yang et al. identify an atypical, clonally expanded population of activated Fc receptor-like 4 (FCRL4)+ B cells that is associated with improved overall survival in patients affected by various tumor types, including BRCA.",

keywords = "ABCs, CD8 cytotoxic T lymphocytes, TNBC, antigen presentation, germinal center, tertiary lymphoid structures, Lymphocytes, Tumor-Infiltrating/immunology, B-Lymphocytes/immunology, Prognosis, Humans, Breast Neoplasms/immunology, Female",

author = "Esmeralda Garc{\'i}a-Torralba and Lorenzo Galluzzi and Aitziber Buqu{\'e}",

year = "2024",

month = nov,

doi = "10.1016/j.trecan.2024.09.009",

language = "English",

volume = "10",

pages = "990--991",

journal = "Trends in Cancer",

issn = "2405-8033",

publisher = "Cell Press",

number = "11",

}

TY - JOUR

T1 - Prognostic value of atypical B cells in breast cancer

AU - García-Torralba, Esmeralda

AU - Galluzzi, Lorenzo

AU - Buqué, Aitziber

PY - 2024/11

Y1 - 2024/11

N2 - The impact of tumor-infiltrating B cells on breast cancer (BRCA) outcomes remains poorly understood. Recent findings from Yang et al. identify an atypical, clonally expanded population of activated Fc receptor-like 4 (FCRL4)+ B cells that is associated with improved overall survival in patients affected by various tumor types, including BRCA.

AB - The impact of tumor-infiltrating B cells on breast cancer (BRCA) outcomes remains poorly understood. Recent findings from Yang et al. identify an atypical, clonally expanded population of activated Fc receptor-like 4 (FCRL4)+ B cells that is associated with improved overall survival in patients affected by various tumor types, including BRCA.

KW - ABCs

KW - CD8 cytotoxic T lymphocytes

KW - TNBC

KW - antigen presentation

KW - germinal center

KW - tertiary lymphoid structures

KW - Lymphocytes, Tumor-Infiltrating/immunology

KW - B-Lymphocytes/immunology

KW - Prognosis

KW - Humans

KW - Breast Neoplasms/immunology

KW - Female

UR - https://www.scopus.com/pages/publications/85205291051

U2 - 10.1016/j.trecan.2024.09.009

DO - 10.1016/j.trecan.2024.09.009

M3 - Article

C2 - 39353814

AN - SCOPUS:85205291051

SN - 2405-8033

VL - 10

SP - 990

EP - 991

JO - Trends in Cancer

JF - Trends in Cancer

IS - 11

ER -

Prognostic value of atypical B cells in breast cancer

Abstract

Keywords

UN SDGs

Access to Document

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