Prognostic value of atypical B cells in breast cancer

Esmeralda García-Torralba, Lorenzo Galluzzi, Aitziber Buqué

Research output: Contribution to journalArticlepeer-review

Abstract

The impact of tumor-infiltrating B cells on breast cancer (BRCA) outcomes remains poorly understood. Recent findings from Yang et al. identify an atypical, clonally expanded population of activated Fc receptor-like 4 (FCRL4)+ B cells that is associated with improved overall survival in patients affected by various tumor types, including BRCA.

Original languageEnglish
Pages (from-to)990-991
Number of pages2
JournalTrends in Cancer
Volume10
Issue number11
DOIs
StatePublished - Nov 2024

Keywords

  • ABCs
  • CD8 cytotoxic T lymphocytes
  • TNBC
  • antigen presentation
  • germinal center
  • tertiary lymphoid structures

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