Pleural malignancies

Joseph S. Friedberg, Keith A. Cengel

Research output: Contribution to journalReview articlepeer-review

12 Scopus citations


Pleural malignancies, primary or metastatic, portend a grim prognosis. In addition to the serious oncologic implications of a pleural malignancy, these tumors can be highly symptomatic. A malignant pleural effusion can cause dyspnea, secondary to lung compression, or even tension physiology from a hydrothorax under pressure. The need to palliate these effusions is a seemingly straightforward clinical scenario, but with nuances that can result in disastrous complications for the patient if not attended to appropriately. Solid pleural malignancies can cause great pain from chest wall invasion or can cause a myriad of morbid symptoms because of the invasion of thoracic structures, such as the heart, lungs, or esophagus. This article reviews pleural malignancies, the purely palliative treatments, and the treatments that are performed with definitive (curative) intent.

Original languageEnglish
Pages (from-to)208-214
Number of pages7
JournalSeminars in Radiation Oncology
Issue number3
StatePublished - Jul 2010
Externally publishedYes


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