Photo-thermal cancer therapy using gold nanorods

E. Fourkal; I. Velchev; A. Taffo; C. Ma; Khazak; N. Skobeleva

doi:10.1007/978-3-642-03885-3_211

Photo-thermal cancer therapy using gold nanorods

E. Fourkal, I. Velchev, A. Taffo, C. Ma, Khazak, N. Skobeleva

Cancer Signaling and Microenvironment (CSM)

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

6 Scopus citations

Abstract

New approaches to treat cancer that are effective with minimal cytotoxicity are needed. We investigate gold nanorods (GNR) in human A-1 ovarian cancer cells to establish: 1) their cytotoxicity effects on cancer cells, 2) laser heating of intracellular GNR to produce thermal damage to malignant cells and 3) effects of combining external therapeutic photon beam with GNR on cancer cells. Different concentration of GNR (10 nm diameter and 40 nm length) were added to cancer cells to access their proliferation as a function of nanorod concentration and laser irradiation time. In addition, the question of how the combination of X-ray radiation and nanoparticles affects cancer cell survival was also addressed.

Original language	English
Title of host publication	World Congress on Medical Physics and Biomedical Engineering
Subtitle of host publication	Diagnostic and Therapeutic Instrumentation, Clinical Engineering
Publisher	Springer Verlag
Pages	761-763
Number of pages	3
Edition	7
ISBN (Print)	9783642038846
DOIs	https://doi.org/10.1007/978-3-642-03885-3_211
State	Published - 2009
Event	World Congress on Medical Physics and Biomedical Engineering: Diagnostic and Therapeutic Instrumentation, Clinical Engineering - Munich, Germany Duration: Sep 7 2009 → Sep 12 2009

Publication series

Name	IFMBE Proceedings
Number	7
Volume	25
ISSN (Print)	1680-0737

Conference

Conference	World Congress on Medical Physics and Biomedical Engineering: Diagnostic and Therapeutic Instrumentation, Clinical Engineering
Country/Territory	Germany
City	Munich
Period	09/7/09 → 09/12/09

Keywords

Gold nanorods
Photo-thermal therapy

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1007/978-3-642-03885-3_211

Cite this

Fourkal, E., Velchev, I., Taffo, A., Ma, C., Khazak, & Skobeleva, N. (2009). Photo-thermal cancer therapy using gold nanorods. In World Congress on Medical Physics and Biomedical Engineering: Diagnostic and Therapeutic Instrumentation, Clinical Engineering (7 ed., pp. 761-763). (IFMBE Proceedings; Vol. 25, No. 7). Springer Verlag. https://doi.org/10.1007/978-3-642-03885-3_211

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abstract = "New approaches to treat cancer that are effective with minimal cytotoxicity are needed. We investigate gold nanorods (GNR) in human A-1 ovarian cancer cells to establish: 1) their cytotoxicity effects on cancer cells, 2) laser heating of intracellular GNR to produce thermal damage to malignant cells and 3) effects of combining external therapeutic photon beam with GNR on cancer cells. Different concentration of GNR (10 nm diameter and 40 nm length) were added to cancer cells to access their proliferation as a function of nanorod concentration and laser irradiation time. In addition, the question of how the combination of X-ray radiation and nanoparticles affects cancer cell survival was also addressed.",

keywords = "Gold nanorods, Photo-thermal therapy",

author = "E. Fourkal and I. Velchev and A. Taffo and C. Ma and Khazak and N. Skobeleva",

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Fourkal, E, Velchev, I, Taffo, A, Ma, C, Khazak & Skobeleva, N 2009, Photo-thermal cancer therapy using gold nanorods. in World Congress on Medical Physics and Biomedical Engineering: Diagnostic and Therapeutic Instrumentation, Clinical Engineering. 7 edn, IFMBE Proceedings, no. 7, vol. 25, Springer Verlag, pp. 761-763, World Congress on Medical Physics and Biomedical Engineering: Diagnostic and Therapeutic Instrumentation, Clinical Engineering, Munich, Germany, 09/7/09. https://doi.org/10.1007/978-3-642-03885-3_211

Photo-thermal cancer therapy using gold nanorods. / Fourkal, E.; Velchev, I.; Taffo, A. et al.
World Congress on Medical Physics and Biomedical Engineering: Diagnostic and Therapeutic Instrumentation, Clinical Engineering. 7. ed. Springer Verlag, 2009. p. 761-763 (IFMBE Proceedings; Vol. 25, No. 7).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

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T1 - Photo-thermal cancer therapy using gold nanorods

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AU - Velchev, I.

AU - Taffo, A.

AU - Ma, C.

AU - Khazak,

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AB - New approaches to treat cancer that are effective with minimal cytotoxicity are needed. We investigate gold nanorods (GNR) in human A-1 ovarian cancer cells to establish: 1) their cytotoxicity effects on cancer cells, 2) laser heating of intracellular GNR to produce thermal damage to malignant cells and 3) effects of combining external therapeutic photon beam with GNR on cancer cells. Different concentration of GNR (10 nm diameter and 40 nm length) were added to cancer cells to access their proliferation as a function of nanorod concentration and laser irradiation time. In addition, the question of how the combination of X-ray radiation and nanoparticles affects cancer cell survival was also addressed.

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Photo-thermal cancer therapy using gold nanorods

Abstract

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Keywords

UN SDGs

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