Phase I study of Aurora a kinase inhibitor MLN8237 in advanced solid tumors: Safety, pharmacokinetics, pharmacodynamics, and bioavailability of two oral formulations

E. Claire Dees, Roger B. Cohen, Margaret Von Mehren, Thomas E. Stinchcombe, Hua Liu, Karthik Venkatakrishnan, Mark Manfredi, Howard Fingert, Howard A. Burris, Jeffrey R. Infante

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Pharmacology, Toxicology and Pharmaceutical Science