Phase I assessment of new mechanism-based pharmacodynamic biomarkers for MLN8054, a small-molecule inhibitor of Aurora A kinase

Arijit Chakravarty, Vaishali Shinde, Josep Tabernero, Andres Cervantes, Roger B. Cohen, E. Claire Dees, Howard Burris, Jeffrey R. Infante, Teresa Macarulla, Elena Elez, Jordi Andreu, Edith Rodriguez-Braun, Susana Rosello, Margaret Von Mehren, Neal J. Meropol, Corey J. Langer, Bert ONeil, Douglas Bowman, Mengkun Zhang, Hadi DanaeeLaura Faron-Yowe, Gary Gray, Hua Liu, Jodi Pappas, Lee Silverman, Chris Simpson, Bradley Stringer, Stephen Tirrell, Ole Petter Veiby, Karthik Venkatakrishnan, Katherine Galvin, Mark Manfredi, Jeffrey A. Ecsedy

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Pharmacology, Toxicology and Pharmaceutical Science