Pelvic Reirradiation Utilizing Pulsed Low-dose Rate Radiation Therapy

Jonathan J. Paly; Mengying Deng; Charles T. Lee; Shelly B. Hayes; Thomas J. Galloway; Mark A. Hallman; Stephanie E. Weiss; Eric M. Horwitz; Robert A. Price; C. M.Charlie Ma; Joshua E. Meyer

doi:10.1097/COC.0000000000000741

Pelvic Reirradiation Utilizing Pulsed Low-dose Rate Radiation Therapy

Jonathan J. Paly, Mengying Deng, Charles T. Lee, Shelly B. Hayes, Thomas J. Galloway, Mark A. Hallman, Stephanie E. Weiss, Eric M. Horwitz, Robert A. Price, C. M.Charlie Ma, Joshua E. Meyer

Fox Chase Cancer Center

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

Pulsed low-dose rate radiation therapy has been shown to reduce normal tissue damage while decreasing DNA damage repair in tumor cells. In a cohort of patients treated with palliative or definitive pelvic reirradiation using pulsed low-dose rate radiation therapy, we observed substantial local control and low rates of toxicity.

Original language	English
Pages (from-to)	748-751
Number of pages	4
Journal	American Journal of Clinical Oncology: Cancer Clinical Trials
Volume	43
Issue number	10
DOIs	https://doi.org/10.1097/COC.0000000000000741
State	Published - Oct 1 2020

Keywords

Adult
Aged
Aged, 80 and over
Female
Humans
Male
Middle Aged
Pelvic Neoplasms/radiotherapy
Radiotherapy Dosage
Re-Irradiation/adverse effects

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1097/COC.0000000000000741

Cite this

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title = "Pelvic Reirradiation Utilizing Pulsed Low-dose Rate Radiation Therapy",

abstract = "Pulsed low-dose rate radiation therapy has been shown to reduce normal tissue damage while decreasing DNA damage repair in tumor cells. In a cohort of patients treated with palliative or definitive pelvic reirradiation using pulsed low-dose rate radiation therapy, we observed substantial local control and low rates of toxicity.",

keywords = "Adult, Aged, Aged, 80 and over, Female, Humans, Male, Middle Aged, Pelvic Neoplasms/radiotherapy, Radiotherapy Dosage, Re-Irradiation/adverse effects",

author = "Paly, {Jonathan J.} and Mengying Deng and Lee, {Charles T.} and Hayes, {Shelly B.} and Galloway, {Thomas J.} and Hallman, {Mark A.} and Weiss, {Stephanie E.} and Horwitz, {Eric M.} and Price, {Robert A.} and Ma, {C. M.Charlie} and Meyer, {Joshua E.}",

year = "2020",

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doi = "10.1097/COC.0000000000000741",

language = "English",

volume = "43",

pages = "748--751",

journal = "American Journal of Clinical Oncology: Cancer Clinical Trials",

issn = "0277-3732",

publisher = "Lippincott Williams and Wilkins Ltd.",

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TY - JOUR

T1 - Pelvic Reirradiation Utilizing Pulsed Low-dose Rate Radiation Therapy

AU - Paly, Jonathan J.

AU - Deng, Mengying

AU - Lee, Charles T.

AU - Hayes, Shelly B.

AU - Galloway, Thomas J.

AU - Hallman, Mark A.

AU - Weiss, Stephanie E.

AU - Horwitz, Eric M.

AU - Price, Robert A.

AU - Ma, C. M.Charlie

AU - Meyer, Joshua E.

PY - 2020/10/1

Y1 - 2020/10/1

N2 - Pulsed low-dose rate radiation therapy has been shown to reduce normal tissue damage while decreasing DNA damage repair in tumor cells. In a cohort of patients treated with palliative or definitive pelvic reirradiation using pulsed low-dose rate radiation therapy, we observed substantial local control and low rates of toxicity.

AB - Pulsed low-dose rate radiation therapy has been shown to reduce normal tissue damage while decreasing DNA damage repair in tumor cells. In a cohort of patients treated with palliative or definitive pelvic reirradiation using pulsed low-dose rate radiation therapy, we observed substantial local control and low rates of toxicity.

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KW - Aged

KW - Aged, 80 and over

KW - Female

KW - Humans

KW - Male

KW - Middle Aged

KW - Pelvic Neoplasms/radiotherapy

KW - Radiotherapy Dosage

KW - Re-Irradiation/adverse effects

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DO - 10.1097/COC.0000000000000741

M3 - Article

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EP - 751

JO - American Journal of Clinical Oncology: Cancer Clinical Trials

JF - American Journal of Clinical Oncology: Cancer Clinical Trials

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ER -

Pelvic Reirradiation Utilizing Pulsed Low-dose Rate Radiation Therapy

Abstract

Keywords

UN SDGs

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Biostatistics and Bioinformatics Facility

Cite this

Pelvic Reirradiation Utilizing Pulsed Low-dose Rate Radiation Therapy

Abstract

Keywords

UN SDGs

Access to Document

Other files and links

Fingerprint

Equipment

Biostatistics and Bioinformatics Facility

Cite this