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Oxaliplatin-induced Immune Thrombocytopenia: A Case Report and Literature Review

  • Temple University
  • Fox Chase Cancer Center

Research output: Contribution to journalArticlepeer-review

14 Scopus citations

Abstract

Oxaliplatin-induced immune thrombocytopenia is a rare manifestation of oxaliplatin hypersensitivity, presenting as an acute onset of severe thrombocytopenia after oxaliplatin administration. No standard therapeutic approach outside of permanent discontinuation of oxaliplatin exists. Here, we present a case of oxaliplatin-induced immune thrombocytopenia occurring after oxaliplatin retreatment for metastatic colon cancer. Possible mechanisms of disease and approach to treatment are discussed.

Original languageEnglish
Pages (from-to)e1-e4
JournalClinical Colorectal Cancer
Volume20
Issue number1
DOIs
StatePublished - Mar 2021

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

Keywords

  • Antineoplastic Combined Chemotherapy Protocols/adverse effects
  • Chemotherapy, Adjuvant/adverse effects
  • Colectomy
  • Colorectal Neoplasms/blood
  • Female
  • Fluorouracil/adverse effects
  • Humans
  • Leucovorin/adverse effects
  • Middle Aged
  • Organoplatinum Compounds/adverse effects
  • Oxaliplatin/adverse effects
  • Thrombocytopenia/blood

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