Abstract
The analysis of 67 cases of benign, progressive, tumor CLL, lymph node lymphocytoma, CLL sarcoma transformation showed that the cases were misdiagnosed in 35.8% cases. The most common mistake (25.4%) was aggressive chemotherapy based on histological diagnosis of prolymphocytic, prolymphocytic-lymphoblastic lymphosarcoma without consideration of cytological and clinical evidence, tumor phenotype. The authors think valid to use the following criteria in diagnosis of lymphoproliferative diseases: histological findings, clinical manifestations and blood picture, tumor cell cytology, primary location and predominant dissemination of the tumor, immunophenotype, characteristic chromosomal disorders, response to treatment.
Translated title of the contribution | Errors in the diagnosis and therapy of chronic lympholeukemias |
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Original language | Russian |
Pages (from-to) | 45-49 |
Number of pages | 5 |
Journal | Terapevticheskii Arkhiv |
Volume | 67 |
Issue number | 7 |
State | Published - 1995 |