Oshibki v diagnostike i terapii khronicheskikh limfoleǐkozov.

Translated title of the contribution: Errors in the diagnosis and therapy of chronic lympholeukemias

E. I. Iakhnina, I. A. Astsaturov, A. V. Pivnik, R. S. Samoǐlova, A. M. Kremenetskaia, A. I. Vorob'ev

Research output: Contribution to journalArticlepeer-review

Abstract

The analysis of 67 cases of benign, progressive, tumor CLL, lymph node lymphocytoma, CLL sarcoma transformation showed that the cases were misdiagnosed in 35.8% cases. The most common mistake (25.4%) was aggressive chemotherapy based on histological diagnosis of prolymphocytic, prolymphocytic-lymphoblastic lymphosarcoma without consideration of cytological and clinical evidence, tumor phenotype. The authors think valid to use the following criteria in diagnosis of lymphoproliferative diseases: histological findings, clinical manifestations and blood picture, tumor cell cytology, primary location and predominant dissemination of the tumor, immunophenotype, characteristic chromosomal disorders, response to treatment.

Translated title of the contributionErrors in the diagnosis and therapy of chronic lympholeukemias
Original languageRussian
Pages (from-to)45-49
Number of pages5
JournalTerapevticheskii Arkhiv
Volume67
Issue number7
StatePublished - 1995

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