Older adult oncology, version 2.2016: Featured updates to the NCCN guidelines

Noam Van Der Walde; Reshma Jagsi; Efrat Dotan; Joel Baumgartner; Ilene S. Browner; Peggy Burhenn; Harvey Jay Cohen; Barish H. Edil; Beatrice Edwards; Martine Extermann; Apar Kishor P. Ganti; Cary Gross; Joleen Hubbard; Nancy L. Keating; Beatriz Korc-Grodzicki; June M. McKoy; Bruno C. Medeiros; Ewa Mrozek; Tracey O'Connor; Hope S. Rugo; Randall W. Rupper; Dale Shepard; Rebecca A. Silliman; Derek L. Stirewalt; William P. Tew; Louise C. Walter; Tanya Wildes; Mary Anne Bergman; Hema Sundar; Arti Hurria

doi:10.6004/jnccn.2016.0146

Older adult oncology, version 2.2016: Featured updates to the NCCN guidelines

Noam Van Der Walde
, Reshma Jagsi
, Efrat Dotan
, Joel Baumgartner
, Ilene S. Browner
, Peggy Burhenn
, Harvey Jay Cohen
, Barish H. Edil
, Beatrice Edwards
, Martine Extermann
, Apar Kishor P. Ganti
, Cary Gross
, Joleen Hubbard
, Nancy L. Keating
, Beatriz Korc-Grodzicki
, June M. McKoy
, Bruno C. Medeiros
, Ewa Mrozek
, Tracey O'Connor
, Hope S. Rugo

Randall W. Rupper, Dale Shepard, Rebecca A. Silliman, Derek L. Stirewalt, William P. Tew, Louise C. Walter, Tanya Wildes, Mary Anne Bergman, Hema Sundar, Arti Hurria

University of Tennessee Health Science Center
University of Michigan, Ann Arbor
University of California at San Diego
Johns Hopkins University
City of Hope National Medical Center
Duke University
University of Colorado
University of Texas MD Anderson Cancer Center
University of South Florida
University of Nebraska Medical Center
Yale University
Mayo Clinic
Dana-Farber/Brigham and Women's Cancer Center
Memorial Sloan-Kettering Cancer Center
Northwestern University
Stanford University
Ohio State University
Roswell Park Cancer Institute
University of California at San Francisco
University of Utah
Case Western Reserve University
Seattle Cancer Care Alliance
Washington University St. Louis
National Comprehensive Cancer Network

Research output: Contribution to journal › Review article › peer-review

91 Scopus citations

Abstract

Cancer is the leading cause of death in older adults aged 60 to 79 years. Older patients with good performance status are able to tolerate commonly used treatment modalities as well as younger patients, particularly when adequate supportive care is provided. For older patients who are able to tolerate curative treatment, options include surgery, radiation therapy (RT), chemotherapy, and targeted therapies. RT can be highly effective and well tolerated in carefully selected patients, and advanced age alone should not preclude the use of RT in older patients with cancer. Judicious application of advanced RT techniques that facilitate normal tissue sparing and reduce RT doses to organs at risk are important for all patients, and may help to assuage concerns about the risks of RT in older adults. These NCCN Guidelines Insights focus on the recent updates to the 2016 NCCN Guidelines for Older Adult Oncology specific to the use of RT in the management of older adults with cancer.

Original language	English
Pages (from-to)	1357-1370
Number of pages	14
Journal	Journal of the National Comprehensive Cancer Network : JNCCN
Volume	14
Issue number	11
DOIs	https://doi.org/10.6004/jnccn.2016.0146
State	Published - Nov 1 2016

Keywords

Aged
Aged, 80 and over
Humans
Medical Oncology

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10.6004/jnccn.2016.0146

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Van Der Walde, N., Jagsi, R., Dotan, E., Baumgartner, J., Browner, I. S., Burhenn, P., Cohen, H. J., Edil, B. H., Edwards, B., Extermann, M., Ganti, A. K. P., Gross, C., Hubbard, J., Keating, N. L., Korc-Grodzicki, B., McKoy, J. M., Medeiros, B. C., Mrozek, E., O'Connor, T., ... Hurria, A. (2016). Older adult oncology, version 2.2016: Featured updates to the NCCN guidelines. Journal of the National Comprehensive Cancer Network : JNCCN, 14(11), 1357-1370. https://doi.org/10.6004/jnccn.2016.0146

@article{cf1ef065915f469aa47ac0b1b49f5b90,

title = "Older adult oncology, version 2.2016: Featured updates to the NCCN guidelines",

abstract = "Cancer is the leading cause of death in older adults aged 60 to 79 years. Older patients with good performance status are able to tolerate commonly used treatment modalities as well as younger patients, particularly when adequate supportive care is provided. For older patients who are able to tolerate curative treatment, options include surgery, radiation therapy (RT), chemotherapy, and targeted therapies. RT can be highly effective and well tolerated in carefully selected patients, and advanced age alone should not preclude the use of RT in older patients with cancer. Judicious application of advanced RT techniques that facilitate normal tissue sparing and reduce RT doses to organs at risk are important for all patients, and may help to assuage concerns about the risks of RT in older adults. These NCCN Guidelines Insights focus on the recent updates to the 2016 NCCN Guidelines for Older Adult Oncology specific to the use of RT in the management of older adults with cancer.",

keywords = "Aged, Aged, 80 and over, Humans, Medical Oncology",

author = "\{Van Der Walde\}, Noam and Reshma Jagsi and Efrat Dotan and Joel Baumgartner and Browner, \{Ilene S.\} and Peggy Burhenn and Cohen, \{Harvey Jay\} and Edil, \{Barish H.\} and Beatrice Edwards and Martine Extermann and Ganti, \{Apar Kishor P.\} and Cary Gross and Joleen Hubbard and Keating, \{Nancy L.\} and Beatriz Korc-Grodzicki and McKoy, \{June M.\} and Medeiros, \{Bruno C.\} and Ewa Mrozek and Tracey O'Connor and Rugo, \{Hope S.\} and Rupper, \{Randall W.\} and Dale Shepard and Silliman, \{Rebecca A.\} and Stirewalt, \{Derek L.\} and Tew, \{William P.\} and Walter, \{Louise C.\} and Tanya Wildes and Bergman, \{Mary Anne\} and Hema Sundar and Arti Hurria",

note = "Copyright {\textcopyright} 2016 by the National Comprehensive Cancer Network.",

year = "2016",

month = nov,

day = "1",

doi = "10.6004/jnccn.2016.0146",

language = "English",

volume = "14",

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journal = "Journal of the National Comprehensive Cancer Network : JNCCN",

issn = "1540-1405",

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Van Der Walde, N, Jagsi, R, Dotan, E, Baumgartner, J, Browner, IS, Burhenn, P, Cohen, HJ, Edil, BH, Edwards, B, Extermann, M, Ganti, AKP, Gross, C, Hubbard, J, Keating, NL, Korc-Grodzicki, B, McKoy, JM, Medeiros, BC, Mrozek, E, O'Connor, T, Rugo, HS, Rupper, RW, Shepard, D, Silliman, RA, Stirewalt, DL, Tew, WP, Walter, LC, Wildes, T, Bergman, MA, Sundar, H & Hurria, A 2016, 'Older adult oncology, version 2.2016: Featured updates to the NCCN guidelines', Journal of the National Comprehensive Cancer Network : JNCCN, vol. 14, no. 11, pp. 1357-1370. https://doi.org/10.6004/jnccn.2016.0146

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T2 - Featured updates to the NCCN guidelines

AU - Van Der Walde, Noam

AU - Jagsi, Reshma

AU - Dotan, Efrat

AU - Baumgartner, Joel

AU - Browner, Ilene S.

AU - Burhenn, Peggy

AU - Cohen, Harvey Jay

AU - Edil, Barish H.

AU - Edwards, Beatrice

AU - Extermann, Martine

AU - Ganti, Apar Kishor P.

AU - Gross, Cary

AU - Hubbard, Joleen

AU - Keating, Nancy L.

AU - Korc-Grodzicki, Beatriz

AU - McKoy, June M.

AU - Medeiros, Bruno C.

AU - Mrozek, Ewa

AU - O'Connor, Tracey

AU - Rugo, Hope S.

AU - Rupper, Randall W.

AU - Shepard, Dale

AU - Silliman, Rebecca A.

AU - Stirewalt, Derek L.

AU - Tew, William P.

AU - Walter, Louise C.

AU - Wildes, Tanya

AU - Bergman, Mary Anne

AU - Sundar, Hema

AU - Hurria, Arti

PY - 2016/11/1

Y1 - 2016/11/1

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AB - Cancer is the leading cause of death in older adults aged 60 to 79 years. Older patients with good performance status are able to tolerate commonly used treatment modalities as well as younger patients, particularly when adequate supportive care is provided. For older patients who are able to tolerate curative treatment, options include surgery, radiation therapy (RT), chemotherapy, and targeted therapies. RT can be highly effective and well tolerated in carefully selected patients, and advanced age alone should not preclude the use of RT in older patients with cancer. Judicious application of advanced RT techniques that facilitate normal tissue sparing and reduce RT doses to organs at risk are important for all patients, and may help to assuage concerns about the risks of RT in older adults. These NCCN Guidelines Insights focus on the recent updates to the 2016 NCCN Guidelines for Older Adult Oncology specific to the use of RT in the management of older adults with cancer.

KW - Aged

KW - Aged, 80 and over

KW - Humans

KW - Medical Oncology

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M3 - Review article

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SN - 1540-1405

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JO - Journal of the National Comprehensive Cancer Network : JNCCN

JF - Journal of the National Comprehensive Cancer Network : JNCCN

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ER -

Older adult oncology, version 2.2016: Featured updates to the NCCN guidelines

Abstract

Keywords

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