Notch receptor inhibition reveals the importance of cyclin D1 and Wnt signaling in invasive esophageal squamous cell carcinoma

S Naganuma, KA Whelan, M Natsuizaka, S Kagawa, H Kinugasa, S Chang, H Subramanian, B Rhoades, S Ohashi, H Itoh, M Herlyn, JA Diehl, PA Gimotty, AJ Klein-Szanto, H Nakagawa

Research output: Contribution to journalArticlepeer-review

Original languageAmerican English
Pages (from-to)459-475
Number of pages17
JournalAmerican Journal of Cancer Research
Volume2
Issue number4
StatePublished - 2012

Keywords

  • 4-Nitroquinoline 1-oxide
  • EGFR
  • Esophageal squamous cell carcinoma
  • Notch
  • P53
  • Wnt
  • Cyclin D1
  • Invasion
  • Organotypic 3D culture
  • Squamous-cell differentiation

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