Normal Variants and Pitfalls Encountered in PET Assessment of Gynecologic Malignancies

Jian Q Yu; Mohan Doss; R Katherine Alpaugh

doi:10.1016/j.cpet.2017.11.009

Normal Variants and Pitfalls Encountered in PET Assessment of Gynecologic Malignancies

Jian Q Yu, Mohan Doss, R Katherine Alpaugh

Fox Chase Cancer Center

Research output: Contribution to journal › Review article › peer-review

3 Scopus citations

Abstract

Combined PET/computed tomography is used for oncological indications. PET/computed tomography benefits from the metabolic information of PET and the anatomic localization of computed tomography. The integrated scanner provides data with accurate registration of anatomy and molecular information. Many physiologic conditions, normal variants, and benign lesions within the pelvis and the body can cause confusion and uncertainty. False-negative results owing to low 18F-fluorodeoxyglucose uptake from the tumor can produce diagnostic challenges and inaccurate conclusions. This article reviews normal variants and potential pitfalls encountered in PET assessment of gynecologic malignancies to provide useful information for the referring and reporting physicians.

Original language	English
Pages (from-to)	249-268
Number of pages	20
Journal	PET Clinics
Volume	13
Issue number	2
DOIs	https://doi.org/10.1016/j.cpet.2017.11.009
State	Published - Mar 2018

Keywords

Adult
Aged
Artifacts
False Positive Reactions
Female
Fluorodeoxyglucose F18
Genital Diseases, Female/diagnostic imaging
Genital Neoplasms, Female/diagnostic imaging
Humans
Middle Aged
Positron Emission Tomography Computed Tomography/adverse effects
Positron-Emission Tomography/adverse effects
Radiographic Image Enhancement
Risk Assessment
Sensitivity and Specificity

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10.1016/j.cpet.2017.11.009

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title = "Normal Variants and Pitfalls Encountered in PET Assessment of Gynecologic Malignancies",

abstract = "Combined PET/computed tomography is used for oncological indications. PET/computed tomography benefits from the metabolic information of PET and the anatomic localization of computed tomography. The integrated scanner provides data with accurate registration of anatomy and molecular information. Many physiologic conditions, normal variants, and benign lesions within the pelvis and the body can cause confusion and uncertainty. False-negative results owing to low 18F-fluorodeoxyglucose uptake from the tumor can produce diagnostic challenges and inaccurate conclusions. This article reviews normal variants and potential pitfalls encountered in PET assessment of gynecologic malignancies to provide useful information for the referring and reporting physicians.",

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author = "Yu, {Jian Q} and Mohan Doss and Alpaugh, {R Katherine}",

year = "2018",

month = mar,

doi = "10.1016/j.cpet.2017.11.009",

language = "English",

volume = "13",

pages = "249--268",

journal = "PET Clinics",

issn = "1556-8598",

publisher = "W.B. Saunders",

number = "2",

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TY - JOUR

T1 - Normal Variants and Pitfalls Encountered in PET Assessment of Gynecologic Malignancies

AU - Yu, Jian Q

AU - Doss, Mohan

AU - Alpaugh, R Katherine

PY - 2018/3

Y1 - 2018/3

N2 - Combined PET/computed tomography is used for oncological indications. PET/computed tomography benefits from the metabolic information of PET and the anatomic localization of computed tomography. The integrated scanner provides data with accurate registration of anatomy and molecular information. Many physiologic conditions, normal variants, and benign lesions within the pelvis and the body can cause confusion and uncertainty. False-negative results owing to low 18F-fluorodeoxyglucose uptake from the tumor can produce diagnostic challenges and inaccurate conclusions. This article reviews normal variants and potential pitfalls encountered in PET assessment of gynecologic malignancies to provide useful information for the referring and reporting physicians.

AB - Combined PET/computed tomography is used for oncological indications. PET/computed tomography benefits from the metabolic information of PET and the anatomic localization of computed tomography. The integrated scanner provides data with accurate registration of anatomy and molecular information. Many physiologic conditions, normal variants, and benign lesions within the pelvis and the body can cause confusion and uncertainty. False-negative results owing to low 18F-fluorodeoxyglucose uptake from the tumor can produce diagnostic challenges and inaccurate conclusions. This article reviews normal variants and potential pitfalls encountered in PET assessment of gynecologic malignancies to provide useful information for the referring and reporting physicians.

KW - Adult

KW - Aged

KW - Artifacts

KW - False Positive Reactions

KW - Female

KW - Fluorodeoxyglucose F18

KW - Genital Diseases, Female/diagnostic imaging

KW - Genital Neoplasms, Female/diagnostic imaging

KW - Humans

KW - Middle Aged

KW - Positron Emission Tomography Computed Tomography/adverse effects

KW - Positron-Emission Tomography/adverse effects

KW - Radiographic Image Enhancement

KW - Risk Assessment

KW - Sensitivity and Specificity

U2 - 10.1016/j.cpet.2017.11.009

DO - 10.1016/j.cpet.2017.11.009

M3 - Review article

C2 - 29482753

SN - 1556-8598

VL - 13

SP - 249

EP - 268

JO - PET Clinics

JF - PET Clinics

IS - 2

ER -

Normal Variants and Pitfalls Encountered in PET Assessment of Gynecologic Malignancies

Abstract

Keywords

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