Abstract
Aculeacin A acylase from Actinoplanes utahensis produced by Streptomyces lividans revealed acylase activities that are able to hydrolyze penicillin V and several natural aliphatic penicillins. Penicillin K was the best substrate, showing a catalytic efficiency of 34.79 mM-1 s-1. Furthermore, aculeacin A acylase was highly thermostable, with a midpoint transition temperature of 81.5°C.
Original language | English |
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Pages (from-to) | 5378-5381 |
Number of pages | 4 |
Journal | Applied and Environmental Microbiology |
Volume | 73 |
Issue number | 16 |
DOIs | |
State | Published - Aug 2007 |