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Neoadjuvant chemotherapy in early-stage non-small cell lung cancer

  • University of Maryland

Research output: Contribution to journalReview articlepeer-review

1 Scopus citations

Abstract

Of the patients that undergo complete resection of early-stage non-small cell lung cancer (NSCLC), 30-60% will die. Postoperative adjuvant chemotherapy has yet to demonstrate an unequivocal benefit and there are significant difficulties in administering postoperative chemotherapy to patients with the significant comorbidities found in NSCLC. Currently, several trials are evaluating the role of preoperative chemotherapy in stage I and II NSCLC. This paper reviews the rationale for this approach and potential future developments.

Original languageEnglish
Pages (from-to)229-235
Number of pages7
JournalExpert Review of Anticancer Therapy
Volume1
Issue number2
DOIs
StatePublished - 2001

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

Keywords

  • Antineoplastic Combined Chemotherapy Protocols/therapeutic use
  • Biomarkers, Tumor/metabolism
  • Carcinoma, Non-Small-Cell Lung/classification
  • Chemotherapy, Adjuvant/methods
  • Clinical Trials as Topic
  • Humans
  • Lung Neoplasms/classification
  • Neoadjuvant Therapy/methods
  • Neoplasm Staging
  • Recurrence

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