Necrosis: Linking the Inflammasome to Inflammation

Lorenzo Galluzzi; José Manuel Bravo-San Pedro; Guido Kroemer

doi:10.1016/j.celrep.2015.05.041

Necrosis: Linking the Inflammasome to Inflammation

Lorenzo Galluzzi, José Manuel Bravo-San Pedro, Guido Kroemer

Research output: Contribution to journal › Short survey › peer-review

7 Scopus citations

Abstract

In this issue of Cell Reports, Cullen et al. demonstrate that the release of mature interleukin-1β relies on necrotic plasma membrane permeabilization. Thus, caspases may have evolved to modulate the inflammatory potential of cell death, not to execute it.

Original language	English
Pages (from-to)	1501-1502
Number of pages	2
Journal	Cell Reports
Volume	11
Issue number	10
DOIs	https://doi.org/10.1016/j.celrep.2015.05.041
State	Published - Jun 16 2015
Externally published	Yes

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10.1016/j.celrep.2015.05.041

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@article{6319892da90f4790971dde327f362eea,

title = "Necrosis: Linking the Inflammasome to Inflammation",

abstract = "In this issue of Cell Reports, Cullen et al. demonstrate that the release of mature interleukin-1β relies on necrotic plasma membrane permeabilization. Thus, caspases may have evolved to modulate the inflammatory potential of cell death, not to execute it.",

author = "Lorenzo Galluzzi and {Bravo-San Pedro}, {Jos{\'e} Manuel} and Guido Kroemer",

note = "Publisher Copyright: {\textcopyright} 2015 The Authors.",

year = "2015",

month = jun,

day = "16",

doi = "10.1016/j.celrep.2015.05.041",

language = "English",

volume = "11",

pages = "1501--1502",

journal = "Cell Reports",

issn = "2211-1247",

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TY - JOUR

T1 - Necrosis

T2 - Linking the Inflammasome to Inflammation

AU - Galluzzi, Lorenzo

AU - Bravo-San Pedro, José Manuel

AU - Kroemer, Guido

PY - 2015/6/16

Y1 - 2015/6/16

N2 - In this issue of Cell Reports, Cullen et al. demonstrate that the release of mature interleukin-1β relies on necrotic plasma membrane permeabilization. Thus, caspases may have evolved to modulate the inflammatory potential of cell death, not to execute it.

AB - In this issue of Cell Reports, Cullen et al. demonstrate that the release of mature interleukin-1β relies on necrotic plasma membrane permeabilization. Thus, caspases may have evolved to modulate the inflammatory potential of cell death, not to execute it.

UR - http://www.scopus.com/inward/record.url?scp=84937571008&partnerID=8YFLogxK

U2 - 10.1016/j.celrep.2015.05.041

DO - 10.1016/j.celrep.2015.05.041

M3 - Short survey

C2 - 26082972

AN - SCOPUS:84937571008

SN - 2211-1247

VL - 11

SP - 1501

EP - 1502

JO - Cell Reports

JF - Cell Reports

IS - 10

ER -

Necrosis: Linking the Inflammasome to Inflammation

Abstract

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