Necroptosis: A Specialized Pathway of Programmed Necrosis

Lorenzo Galluzzi; Guido Kroemer

doi:10.1016/j.cell.2008.12.004

Necroptosis: A Specialized Pathway of Programmed Necrosis

Lorenzo Galluzzi, Guido Kroemer

Cancer Signaling and Microenvironment (CSM)

Research output: Contribution to journal › Short survey › peer-review

468 Scopus citations

Abstract

Necrosis is often viewed as an accidental and unregulated cellular event. However, accumulating evidence suggests that necrosis, like apoptosis, can be executed by regulated mechanisms. Hitomi et al. (2008) now describe an extensive network of genes that mediate a form of programmed necrosis called necroptosis.

Original language	English
Pages (from-to)	1161-1163
Number of pages	3
Journal	Cell
Volume	135
Issue number	7
DOIs	https://doi.org/10.1016/j.cell.2008.12.004
State	Published - Dec 26 2008

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title = "Necroptosis: A Specialized Pathway of Programmed Necrosis",

abstract = "Necrosis is often viewed as an accidental and unregulated cellular event. However, accumulating evidence suggests that necrosis, like apoptosis, can be executed by regulated mechanisms. Hitomi et al. (2008) now describe an extensive network of genes that mediate a form of programmed necrosis called necroptosis.",

author = "Lorenzo Galluzzi and Guido Kroemer",

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doi = "10.1016/j.cell.2008.12.004",

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T1 - Necroptosis

T2 - A Specialized Pathway of Programmed Necrosis

AU - Galluzzi, Lorenzo

AU - Kroemer, Guido

PY - 2008/12/26

Y1 - 2008/12/26

N2 - Necrosis is often viewed as an accidental and unregulated cellular event. However, accumulating evidence suggests that necrosis, like apoptosis, can be executed by regulated mechanisms. Hitomi et al. (2008) now describe an extensive network of genes that mediate a form of programmed necrosis called necroptosis.

AB - Necrosis is often viewed as an accidental and unregulated cellular event. However, accumulating evidence suggests that necrosis, like apoptosis, can be executed by regulated mechanisms. Hitomi et al. (2008) now describe an extensive network of genes that mediate a form of programmed necrosis called necroptosis.

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U2 - 10.1016/j.cell.2008.12.004

DO - 10.1016/j.cell.2008.12.004

M3 - Short survey

C2 - 19109884

AN - SCOPUS:57649167477

SN - 0092-8674

VL - 135

SP - 1161

EP - 1163

JO - Cell

JF - Cell

IS - 7

ER -

Necroptosis: A Specialized Pathway of Programmed Necrosis

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