Abstract
BACKGROUND: Mycosis fungoides primarily localized to the palms and soles is rare and has been previously reported as cutaneous lymphoma in four patients or as Woringer-Kolopp disease in eight patients.
OBSERVATIONS: Four patients were initially diagnosed and treated unsuccessfully for various palmoplantar dermatitides until histopathologic findings revealed mycosis fungoides. Each case exhibited a clonal rearrangement of T-cell receptor gamma genes and immunohistochemical studies consonant with mycosis fungoides. All patients had limited skin involvement without evidence of extracutaneous involvement.
CONCLUSIONS: Mycosis fungoides palmaris et plantaris is an uncommon expression of mycosis fungoides that manifests primarily on the palms and soles and clinically may mimic various inflammatory palmoplantar dermatoses. A biopsy is recommended in the evaluation of recalcitrant palmoplantar dermatoses.
Original language | English |
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Pages (from-to) | 1052-1056 |
Number of pages | 5 |
Journal | Archives of Dermatology |
Volume | 131 |
Issue number | 9 |
DOIs | |
State | Published - Sep 1995 |
Keywords
- Diagnosis, Differential
- Female
- Foot Dermatoses/diagnosis
- Foot Diseases/pathology
- Hand
- Hand Dermatoses/diagnosis
- Humans
- Middle Aged
- Mycosis Fungoides/diagnosis
- Skin Neoplasms/diagnosis