Multifunctional nanoparticles for prostate cancer therapy

Carolina Salvador-Morales, Weiwei Gao, Pooja Ghatalia, Farhan Murshed, Wataru Aizu, Robert Langer, Omid C. Farokhzad

Research output: Contribution to journalReview articlepeer-review

26 Scopus citations

Abstract

Multifunctional nanoparticles promise significantly better treatment for prostate cancer. This review begins with a molecular and physiological overview of prostate cancer, including current treatments in various stages of disease development. Emerging nanoparticle technology in chemotherapy, hyperthermia therapy and gene therapy will be discussed. We highlight novel advances in nanoparticle technology for prostate cancer and indicate future challenges in the rational design of multifunctional nanoparticles, such as understanding tumor characteristics and the activation of the complement system.

Original languageEnglish
Pages (from-to)211-221
Number of pages11
JournalExpert Review of Anticancer Therapy
Volume9
Issue number2
DOIs
StatePublished - 2009

Keywords

  • Chemotherapy
  • Gene therapy
  • Hyperthermia
  • Multifunctional
  • Nanoparticle
  • Prostate cancer

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