TY - JOUR
T1 - MR imaging characteristics of noncancerous lesions of the prostate
AU - Lovett, Karen
AU - Rifkin, Matthew D.
AU - McCue, Peter A.
AU - Choi, Hong
PY - 1992
Y1 - 1992
N2 - Radical prostatectomy specimens from 53 men with clinical stage A or B prostate cancer were retrospectively reviewed and compared with correlative axial T2‐weighted magnetic resonance (MR) images obtained just before surgery. Non‐cancerous lesions were evaluated for signal intensity and location. Focal high‐signal‐intensity areas (n = 72) were present in 81% of patients. The 26% of lesions seen in the central gland all correlated with cystic atrophy. Of the 53 lesions seen in the peripheral prostate, 47 (89%) were cystic atrophy without associated cancer, four (7.5%) cystic atrophy with cancer, and two (3.8%) focal inflammation. Focal low‐signal‐intensity areas (n = 42) were present in 60% of patients. Of the 31% of lesions in the central prostate, one‐fifth correlated with benign prostatic hyperplasia (BPH) and four‐fifths with fibrous tissue. Of the 69% of peripheral lesions, 83% corresponded to fibrous tissue, 10% to BPH, and 7% to normal tissue. Mixed lesions (n = 42) were present in 64% of patients; 86% of these were located centrally and 14% peripherally. All mixed central lesions were BPH; the peripheral lesions were areas of combined cystic atrophy and fibrosis. BPH of low or mixed signal intensity can extend into the peripheral prostate and mimic cancer. High‐intensity cystic atrophy associated with cancer can mimic normal tissue.
AB - Radical prostatectomy specimens from 53 men with clinical stage A or B prostate cancer were retrospectively reviewed and compared with correlative axial T2‐weighted magnetic resonance (MR) images obtained just before surgery. Non‐cancerous lesions were evaluated for signal intensity and location. Focal high‐signal‐intensity areas (n = 72) were present in 81% of patients. The 26% of lesions seen in the central gland all correlated with cystic atrophy. Of the 53 lesions seen in the peripheral prostate, 47 (89%) were cystic atrophy without associated cancer, four (7.5%) cystic atrophy with cancer, and two (3.8%) focal inflammation. Focal low‐signal‐intensity areas (n = 42) were present in 60% of patients. Of the 31% of lesions in the central prostate, one‐fifth correlated with benign prostatic hyperplasia (BPH) and four‐fifths with fibrous tissue. Of the 69% of peripheral lesions, 83% corresponded to fibrous tissue, 10% to BPH, and 7% to normal tissue. Mixed lesions (n = 42) were present in 64% of patients; 86% of these were located centrally and 14% peripherally. All mixed central lesions were BPH; the peripheral lesions were areas of combined cystic atrophy and fibrosis. BPH of low or mixed signal intensity can extend into the peripheral prostate and mimic cancer. High‐intensity cystic atrophy associated with cancer can mimic normal tissue.
KW - Prostate, MR, 844.1214
KW - Prostate, cysts, 844.311
KW - Prostate, hyperplasia, 844.316
KW - Prostate, neoplasms, 844.32
KW - Tissue characterization
UR - http://www.scopus.com/inward/record.url?scp=0026494373&partnerID=8YFLogxK
UR - https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=purepublist2023&SrcAuth=WosAPI&KeyUT=WOS:A1992HB35100005&DestLinkType=FullRecord&DestApp=WOS
U2 - 10.1002/jmri.1880020106
DO - 10.1002/jmri.1880020106
M3 - Article
C2 - 1377976
SN - 1053-1807
VL - 2
SP - 35
EP - 39
JO - Journal of Magnetic Resonance Imaging
JF - Journal of Magnetic Resonance Imaging
IS - 1
ER -