Modeling Tissue Morphogenesis and Cancer in 3D

Kenneth M. Yamada, Edna Cukierman

Research output: Contribution to journalReview articlepeer-review

1494 Scopus citations

Abstract

Three-dimensional (3D) in vitro models span the gap between two-dimensional cell cultures and whole-animal systems. By mimicking features of the in vivo environment and taking advantage of the same tools used to study cells in traditional cell culture, 3D models provide unique perspectives on the behavior of stem cells, developing tissues and organs, and tumors. These models may help to accelerate translational research in cancer biology and tissue engineering.

Original languageEnglish
Pages (from-to)601-610
Number of pages10
JournalCell
Volume130
Issue number4
DOIs
StatePublished - Aug 24 2007

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