Modeling collective cell behavior in cancer: Perspectives from an interdisciplinary conversation

Frederick R. Adler; Alexander R.A. Anderson; Abhinav Bhushan; Paul Bogdan; Jose Javier Bravo-Cordero; Amy Brock; Yun Chen; Edna Cukierman; Kathleen E. DelGiorno; Gerald V. Denis; Meghan C. Ferrall-Fairbanks; Zev Jordan Gartner; Ronald N. Germain; Deborah M. Gordon; Ginger Hunter; Mohit Kumar Jolly; Loukia Georgiou Karacosta; Karthikeyan Mythreye; Parag Katira; Rajan P. Kulkarni; Matthew L. Kutys; Arthur D. Lander; Ashley M. Laughney; Herbert Levine; Emil Lou; Pedro R. Lowenstein; Kristyn S. Masters; Dana Pe'er; Shelly R. Peyton; Manu O. Platt; Jeremy E. Purvis; Gerald Quon; Jennifer K. Richer; Nicole C. Riddle; Analiz Rodriguez; Joshua C. Snyder; Gregory Lee Szeto; Claire J. Tomlin; Itai Yanai; Ioannis K. Zervantonakis; Hannah Dueck

doi:10.1016/j.cels.2023.03.002

Modeling collective cell behavior in cancer: Perspectives from an interdisciplinary conversation

Frederick R. Adler
, Alexander R.A. Anderson
, Abhinav Bhushan
, Paul Bogdan
, Jose Javier Bravo-Cordero
, Amy Brock
, Yun Chen
, Edna Cukierman
, Kathleen E. DelGiorno
, Gerald V. Denis
, Meghan C. Ferrall-Fairbanks
, Zev Jordan Gartner
, Ronald N. Germain
, Deborah M. Gordon
, Ginger Hunter
, Mohit Kumar Jolly
, Loukia Georgiou Karacosta
, Karthikeyan Mythreye
, Parag Katira
, Rajan P. Kulkarni

Matthew L. Kutys, Arthur D. Lander, Ashley M. Laughney, Herbert Levine, Emil Lou, Pedro R. Lowenstein, Kristyn S. Masters, Dana Pe'er, Shelly R. Peyton, Manu O. Platt, Jeremy E. Purvis, Gerald Quon, Jennifer K. Richer, Nicole C. Riddle, Analiz Rodriguez, Joshua C. Snyder, Gregory Lee Szeto, Claire J. Tomlin, Itai Yanai, Ioannis K. Zervantonakis, Hannah Dueck

University of Utah
Illinois Institute of Technology
University of Southern California
Icahn School of Medicine at Mount Sinai
University of Texas at Austin
Johns Hopkins University
Temple University
Vanderbilt University
Boston University
University of Florida
University of California at San Francisco
National Institutes of Health
Stanford University
Clarkson University
Indian Institute of Science Bangalore
University of Texas MD Anderson Cancer Center
University of Alabama at Birmingham
San Diego State University
Oregon Health and Science University
University of California at Irvine
Cornell University
Northeastern University
University of Minnesota Twin Cities
University of Michigan, Ann Arbor
University of Wisconsin-Madison
Memorial Sloan-Kettering Cancer Center
University of Massachusetts
Emory University
University of North Carolina at Chapel Hill
University of California at Davis
University of Colorado Anschutz Medical Campus
University of Arkansas for Medical Sciences
Duke University
Allen Institute for Immunology
University of California at Berkeley
New York University
University of Pittsburgh
Moffitt Cancer Center

Research output: Contribution to journal › Comment/debate

7 Scopus citations

Abstract

Collective cell behavior contributes to all stages of cancer progression. Understanding how collective behavior emerges through cell-cell interactions and decision-making will advance our understanding of cancer biology and provide new therapeutic approaches. Here, we summarize an interdisciplinary discussion on multicellular behavior in cancer, draw lessons from other scientific disciplines, and identify future directions.

Original language	English
Pages (from-to)	252-257
Number of pages	6
Journal	Cell Systems
Volume	14
Issue number	4
DOIs	https://doi.org/10.1016/j.cels.2023.03.002
State	Published - Apr 19 2023

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Humans
Mass Behavior
Neoplasms
Communication

Access to Document

10.1016/j.cels.2023.03.002

Cite this

Adler, F. R., Anderson, A. R. A., Bhushan, A., Bogdan, P., Bravo-Cordero, J. J., Brock, A., Chen, Y., Cukierman, E., DelGiorno, K. E., Denis, G. V., Ferrall-Fairbanks, M. C., Gartner, Z. J., Germain, R. N., Gordon, D. M., Hunter, G., Jolly, M. K., Karacosta, L. G., Mythreye, K., Katira, P., ... Dueck, H. (2023). Modeling collective cell behavior in cancer: Perspectives from an interdisciplinary conversation. Cell Systems, 14(4), 252-257. https://doi.org/10.1016/j.cels.2023.03.002

@article{da48477e9ca34a11b0e03869ded34461,

title = "Modeling collective cell behavior in cancer: Perspectives from an interdisciplinary conversation",

abstract = "Collective cell behavior contributes to all stages of cancer progression. Understanding how collective behavior emerges through cell-cell interactions and decision-making will advance our understanding of cancer biology and provide new therapeutic approaches. Here, we summarize an interdisciplinary discussion on multicellular behavior in cancer, draw lessons from other scientific disciplines, and identify future directions.",

keywords = "Humans, Mass Behavior, Neoplasms, Communication",

author = "Adler, \{Frederick R.\} and Anderson, \{Alexander R.A.\} and Abhinav Bhushan and Paul Bogdan and Bravo-Cordero, \{Jose Javier\} and Amy Brock and Yun Chen and Edna Cukierman and DelGiorno, \{Kathleen E.\} and Denis, \{Gerald V.\} and Ferrall-Fairbanks, \{Meghan C.\} and Gartner, \{Zev Jordan\} and Germain, \{Ronald N.\} and Gordon, \{Deborah M.\} and Ginger Hunter and Jolly, \{Mohit Kumar\} and Karacosta, \{Loukia Georgiou\} and Karthikeyan Mythreye and Parag Katira and Kulkarni, \{Rajan P.\} and Kutys, \{Matthew L.\} and Lander, \{Arthur D.\} and Laughney, \{Ashley M.\} and Herbert Levine and Emil Lou and Lowenstein, \{Pedro R.\} and Masters, \{Kristyn S.\} and Dana Pe'er and Peyton, \{Shelly R.\} and Platt, \{Manu O.\} and Purvis, \{Jeremy E.\} and Gerald Quon and Richer, \{Jennifer K.\} and Riddle, \{Nicole C.\} and Analiz Rodriguez and Snyder, \{Joshua C.\} and \{Lee Szeto\}, Gregory and Tomlin, \{Claire J.\} and Itai Yanai and Zervantonakis, \{Ioannis K.\} and Hannah Dueck",

note = "Publisher Copyright: {\textcopyright} 2023",

year = "2023",

month = apr,

day = "19",

doi = "10.1016/j.cels.2023.03.002",

language = "English",

volume = "14",

pages = "252--257",

journal = "Cell Systems",

issn = "2405-4712",

publisher = "Cell Press",

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}

Adler, FR, Anderson, ARA, Bhushan, A, Bogdan, P, Bravo-Cordero, JJ, Brock, A, Chen, Y, Cukierman, E, DelGiorno, KE, Denis, GV, Ferrall-Fairbanks, MC, Gartner, ZJ, Germain, RN, Gordon, DM, Hunter, G, Jolly, MK, Karacosta, LG, Mythreye, K, Katira, P, Kulkarni, RP, Kutys, ML, Lander, AD, Laughney, AM, Levine, H, Lou, E, Lowenstein, PR, Masters, KS, Pe'er, D, Peyton, SR, Platt, MO, Purvis, JE, Quon, G, Richer, JK, Riddle, NC, Rodriguez, A, Snyder, JC, Lee Szeto, G, Tomlin, CJ, Yanai, I, Zervantonakis, IK & Dueck, H 2023, 'Modeling collective cell behavior in cancer: Perspectives from an interdisciplinary conversation', Cell Systems, vol. 14, no. 4, pp. 252-257. https://doi.org/10.1016/j.cels.2023.03.002

TY - JOUR

T1 - Modeling collective cell behavior in cancer

T2 - Perspectives from an interdisciplinary conversation

AU - Adler, Frederick R.

AU - Anderson, Alexander R.A.

AU - Bhushan, Abhinav

AU - Bogdan, Paul

AU - Bravo-Cordero, Jose Javier

AU - Brock, Amy

AU - Chen, Yun

AU - Cukierman, Edna

AU - DelGiorno, Kathleen E.

AU - Denis, Gerald V.

AU - Ferrall-Fairbanks, Meghan C.

AU - Gartner, Zev Jordan

AU - Germain, Ronald N.

AU - Gordon, Deborah M.

AU - Hunter, Ginger

AU - Jolly, Mohit Kumar

AU - Karacosta, Loukia Georgiou

AU - Mythreye, Karthikeyan

AU - Katira, Parag

AU - Kulkarni, Rajan P.

AU - Kutys, Matthew L.

AU - Lander, Arthur D.

AU - Laughney, Ashley M.

AU - Levine, Herbert

AU - Lou, Emil

AU - Lowenstein, Pedro R.

AU - Masters, Kristyn S.

AU - Pe'er, Dana

AU - Peyton, Shelly R.

AU - Platt, Manu O.

AU - Purvis, Jeremy E.

AU - Quon, Gerald

AU - Richer, Jennifer K.

AU - Riddle, Nicole C.

AU - Rodriguez, Analiz

AU - Snyder, Joshua C.

AU - Lee Szeto, Gregory

AU - Tomlin, Claire J.

AU - Yanai, Itai

AU - Zervantonakis, Ioannis K.

AU - Dueck, Hannah

PY - 2023/4/19

Y1 - 2023/4/19

N2 - Collective cell behavior contributes to all stages of cancer progression. Understanding how collective behavior emerges through cell-cell interactions and decision-making will advance our understanding of cancer biology and provide new therapeutic approaches. Here, we summarize an interdisciplinary discussion on multicellular behavior in cancer, draw lessons from other scientific disciplines, and identify future directions.

AB - Collective cell behavior contributes to all stages of cancer progression. Understanding how collective behavior emerges through cell-cell interactions and decision-making will advance our understanding of cancer biology and provide new therapeutic approaches. Here, we summarize an interdisciplinary discussion on multicellular behavior in cancer, draw lessons from other scientific disciplines, and identify future directions.

KW - Humans

KW - Mass Behavior

KW - Neoplasms

KW - Communication

UR - https://www.scopus.com/pages/publications/85152230264

UR - https://pubmed.ncbi.nlm.nih.gov/37080161/

U2 - 10.1016/j.cels.2023.03.002

DO - 10.1016/j.cels.2023.03.002

M3 - Comment/debate

C2 - 37080161

SN - 2405-4712

VL - 14

SP - 252

EP - 257

JO - Cell Systems

JF - Cell Systems

IS - 4

ER -

Modeling collective cell behavior in cancer: Perspectives from an interdisciplinary conversation

Abstract

UN SDGs

Keywords

Access to Document

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Cite this