Metabolic switches in cell death regulation

Lorenzo Galluzzi

doi:10.1016/j.cmet.2025.04.017

Metabolic switches in cell death regulation

Lorenzo Galluzzi

Cancer Signaling and Microenvironment (CSM)

Research output: Contribution to journal › Review article › peer-review

3 Scopus citations

Abstract

The death of mammalian cells is generally regulated by a complex interplay amongst distinct molecular machineries that ultimately determines the kinetic and immunological consequences of the process. Recent data from Song et al. delineate a new metabolic circuitry through which apoptotic signals may actively suppress cell death via ferroptosis.

Original language	English
Pages (from-to)	1252-1254
Number of pages	3
Journal	Cell Metabolism
Volume	37
Issue number	6
DOIs	https://doi.org/10.1016/j.cmet.2025.04.017
State	Published - Jun 3 2025

Keywords

Animals
Apoptosis
Cell Death
Ferroptosis
Humans
Signal Transduction

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10.1016/j.cmet.2025.04.017

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title = "Metabolic switches in cell death regulation",

abstract = "The death of mammalian cells is generally regulated by a complex interplay amongst distinct molecular machineries that ultimately determines the kinetic and immunological consequences of the process. Recent data from Song et al. delineate a new metabolic circuitry through which apoptotic signals may actively suppress cell death via ferroptosis.",

keywords = "Animals, Apoptosis, Cell Death, Ferroptosis, Humans, Signal Transduction",

author = "Lorenzo Galluzzi",

year = "2025",

month = jun,

day = "3",

doi = "10.1016/j.cmet.2025.04.017",

language = "English",

volume = "37",

pages = "1252--1254",

journal = "Cell Metabolism",

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T1 - Metabolic switches in cell death regulation

AU - Galluzzi, Lorenzo

PY - 2025/6/3

Y1 - 2025/6/3

N2 - The death of mammalian cells is generally regulated by a complex interplay amongst distinct molecular machineries that ultimately determines the kinetic and immunological consequences of the process. Recent data from Song et al. delineate a new metabolic circuitry through which apoptotic signals may actively suppress cell death via ferroptosis.

AB - The death of mammalian cells is generally regulated by a complex interplay amongst distinct molecular machineries that ultimately determines the kinetic and immunological consequences of the process. Recent data from Song et al. delineate a new metabolic circuitry through which apoptotic signals may actively suppress cell death via ferroptosis.

KW - Animals

KW - Apoptosis

KW - Cell Death

KW - Ferroptosis

KW - Humans

KW - Signal Transduction

UR - https://www.scopus.com/pages/publications/105006733251

U2 - 10.1016/j.cmet.2025.04.017

DO - 10.1016/j.cmet.2025.04.017

M3 - Review article

C2 - 40466623

AN - SCOPUS:105006733251

SN - 1550-4131

VL - 37

SP - 1252

EP - 1254

JO - Cell Metabolism

JF - Cell Metabolism

IS - 6

ER -

Metabolic switches in cell death regulation

Abstract

Keywords

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