Abstract
Transcription of eukaryotic genes by RNA polymerase II is typically accompanied by minimal exchange of histones H3/H4 carrying various covalent modifications. In vitro studies suggest that histone survival is accompanied by the formation of a small transient DNA loop on the surface of the histone octamer including a molecule of transcribing enzyme.
| Original language | English |
|---|---|
| Pages (from-to) | 85-88 |
| Number of pages | 4 |
| Journal | Transcription |
| Volume | 1 |
| Issue number | 2 |
| DOIs | |
| State | Published - 2010 |
| Externally published | Yes |
Keywords
- Chromatin
- Elongation
- Intermediates
- Mechanism
- Nucleosome
- RNA polymerase II
- Structure
- Transcription