Mapping of AKT3, encoding a member of the Akt/protein kinase B family, to human and rodent chromosomes by fluorescence in situ hybridization

S. S. Murthy; A. Tosolini; T. Taguchi; Joseph R. Testa

doi:10.1159/000015481

Mapping of AKT3, encoding a member of the Akt/protein kinase B family, to human and rodent chromosomes by fluorescence in situ hybridization

S. S. Murthy, A. Tosolini, T. Taguchi, Joseph R. Testa

Cancer Prevention and Control (CPC)

Research output: Contribution to journal › Article › peer-review

47 Scopus citations

Abstract

Previously, a rodent cDNA encoding the third member of the Akt/PKB family of serine/threonine kinases was cloned. We have now cloned the human homolog of this cDNA, and we have used this clone to map the AKT3 gene to human chromosome 1q44 by fluorescence in situ hybridization (FISH). We have also mapped the rodent homologs of AKT3 to rat chromosome 13q24→q26 and mouse chromosome 1H4-6 by FISH. Copyright (C) 2000 S. Karger AG, Basel.

Original language	English
Pages (from-to)	38-40
Number of pages	3
Journal	Cytogenetics and Cell Genetics
Volume	88
Issue number	1-2
DOIs	https://doi.org/10.1159/000015481
State	Published - 2000

Keywords

Animals
Chromosomes, Human, Pair 1/genetics
Cloning, Molecular
Fibroblasts
Humans
In Situ Hybridization, Fluorescence
Lymphocytes
Mice
Multigene Family/genetics
Oncogene Proteins/genetics
Physical Chromosome Mapping
Protein Serine-Threonine Kinases/genetics
Proto-Oncogene Proteins c-akt
Rats
Sequence Homology, Amino Acid

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abstract = "Previously, a rodent cDNA encoding the third member of the Akt/PKB family of serine/threonine kinases was cloned. We have now cloned the human homolog of this cDNA, and we have used this clone to map the AKT3 gene to human chromosome 1q44 by fluorescence in situ hybridization (FISH). We have also mapped the rodent homologs of AKT3 to rat chromosome 13q24→q26 and mouse chromosome 1H4-6 by FISH. Copyright (C) 2000 S. Karger AG, Basel.",

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doi = "10.1159/000015481",

language = "English",

volume = "88",

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journal = "Cytogenetics and Cell Genetics",

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T1 - Mapping of AKT3, encoding a member of the Akt/protein kinase B family, to human and rodent chromosomes by fluorescence in situ hybridization

AU - Murthy, S. S.

AU - Tosolini, A.

AU - Taguchi, T.

AU - Testa, Joseph R.

PY - 2000

Y1 - 2000

N2 - Previously, a rodent cDNA encoding the third member of the Akt/PKB family of serine/threonine kinases was cloned. We have now cloned the human homolog of this cDNA, and we have used this clone to map the AKT3 gene to human chromosome 1q44 by fluorescence in situ hybridization (FISH). We have also mapped the rodent homologs of AKT3 to rat chromosome 13q24→q26 and mouse chromosome 1H4-6 by FISH. Copyright (C) 2000 S. Karger AG, Basel.

AB - Previously, a rodent cDNA encoding the third member of the Akt/PKB family of serine/threonine kinases was cloned. We have now cloned the human homolog of this cDNA, and we have used this clone to map the AKT3 gene to human chromosome 1q44 by fluorescence in situ hybridization (FISH). We have also mapped the rodent homologs of AKT3 to rat chromosome 13q24→q26 and mouse chromosome 1H4-6 by FISH. Copyright (C) 2000 S. Karger AG, Basel.

KW - Animals

KW - Chromosomes, Human, Pair 1/genetics

KW - Cloning, Molecular

KW - Fibroblasts

KW - Humans

KW - In Situ Hybridization, Fluorescence

KW - Lymphocytes

KW - Mice

KW - Multigene Family/genetics

KW - Oncogene Proteins/genetics

KW - Physical Chromosome Mapping

KW - Protein Serine-Threonine Kinases/genetics

KW - Proto-Oncogene Proteins c-akt

KW - Rats

KW - Sequence Homology, Amino Acid

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JO - Cytogenetics and Cell Genetics

JF - Cytogenetics and Cell Genetics

IS - 1-2

ER -

Mapping of AKT3, encoding a member of the Akt/protein kinase B family, to human and rodent chromosomes by fluorescence in situ hybridization

Abstract

Keywords

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