Management of Immunotherapy-Related Toxicities, Version 1.2022, NCCN Clinical Practice Guidelines in Oncology

John A. Thompson; Bryan J. Schneider; Julie Brahmer; Amaka Achufusi; Philippe Armand; Meghan K. Berkenstock; Shailender Bhatia; Lihua E. Budde; Saurin Chokshi; Marianne Davies; Amro Elshoury; Yaron Gesthalter; Aparna Hegde; Michael Jain; Benjamin H. Kaffenberger; Melissa G. Lechner; Tianhong Li; Alissa Marr; Suzanne McGettigan; Jordan McPherson; Theresa Medina; Nisha A. Mohindra; Anthony J. Olszanski; Olalekan Oluwole; Sandip P. Patel; Pradnya Patil; Sunil Reddy; Mabel Ryder; Bianca Santomasso; Scott Shofer; Jeffrey A. Sosman; Yinghong Wang; Vlad G. Zaha; Megan Lyons; Mary Dwyer; Lisa Hang

doi:10.6004/jnccn.2022.0020

Management of Immunotherapy-Related Toxicities, Version 1.2022, NCCN Clinical Practice Guidelines in Oncology

John A. Thompson
, Bryan J. Schneider
, Julie Brahmer
, Amaka Achufusi
, Philippe Armand
, Meghan K. Berkenstock
, Shailender Bhatia
, Lihua E. Budde
, Saurin Chokshi
, Marianne Davies
, Amro Elshoury
, Yaron Gesthalter
, Aparna Hegde
, Michael Jain
, Benjamin H. Kaffenberger
, Melissa G. Lechner
, Tianhong Li
, Alissa Marr
, Suzanne McGettigan
, Jordan McPherson

Theresa Medina, Nisha A. Mohindra, Anthony J. Olszanski, Olalekan Oluwole, Sandip P. Patel, Pradnya Patil, Sunil Reddy, Mabel Ryder, Bianca Santomasso, Scott Shofer, Jeffrey A. Sosman, Yinghong Wang, Vlad G. Zaha, Megan Lyons, Mary Dwyer, Lisa Hang

Seattle Cancer Care Alliance
University of Michigan, Ann Arbor
Johns Hopkins University
University of Wisconsin-Madison
Dana-Farber Cancer Institute
City of Hope National Medical Center
University of Tennessee Health Science Center
Yale University
Roswell Park Comprehensive Cancer Center
University of California at San Francisco
University of Alabama at Birmingham
University of South Florida
Ohio State University
University of California at Los Angeles
University of California at Davis
University of Nebraska Medical Center
University of Pennsylvania
University of Utah
University of Colorado Anschutz Medical Campus
Northwestern University
Vanderbilt University
University of California at San Diego
Case Western Reserve University
Stanford University
Mayo Clinic
Memorial Sloan-Kettering Cancer Center
Duke University
University of Texas MD Anderson Cancer Center
UT Southwestern Simmons Comprehensive Cancer Center
National Comprehensive Cancer Network

Research output: Contribution to journal › Article › peer-review

404 Scopus citations

Abstract

The aim of the NCCN Guidelines for Management of Immunotherapy-Related Toxicities is to provide guidance on the management of immune-related adverse events resulting from cancer immunotherapy. The NCCN Management of Immunotherapy-Related Toxicities Panel is an interdisciplinary group of representatives from NCCN Member Institutions, consisting of medical and hematologic oncologists with expertise across a wide range of disease sites, and experts from the areas of dermatology, gastroenterology, endocrinology, neurooncology, nephrology, cardio-oncology, ophthalmology, pulmonary medicine, and oncology nursing. The content featured in this issue is an excerpt of the recommendations for managing toxicities related to CAR T-cell therapies and a review of existing evidence. For the full version of the NCCN Guidelines, including recommendations for managing toxicities related to immune checkpoint inhibitors, visit NCCN.org.

Original language	English
Pages (from-to)	387-405
Number of pages	19
Journal	Journal of the National Comprehensive Cancer Network : JNCCN
Volume	20
Issue number	4
DOIs	https://doi.org/10.6004/jnccn.2022.0020
State	Published - Apr 2022

Keywords

Humans
Immune Checkpoint Inhibitors
Immunologic Factors/therapeutic use
Immunotherapy/adverse effects
Medical Oncology
Neoplasms/drug therapy

Access to Document

10.6004/jnccn.2022.0020

Cite this

Thompson, J. A., Schneider, B. J., Brahmer, J., Achufusi, A., Armand, P., Berkenstock, M. K., Bhatia, S., Budde, L. E., Chokshi, S., Davies, M., Elshoury, A., Gesthalter, Y., Hegde, A., Jain, M., Kaffenberger, B. H., Lechner, M. G., Li, T., Marr, A., McGettigan, S., ... Hang, L. (2022). Management of Immunotherapy-Related Toxicities, Version 1.2022, NCCN Clinical Practice Guidelines in Oncology. Journal of the National Comprehensive Cancer Network : JNCCN, 20(4), 387-405. https://doi.org/10.6004/jnccn.2022.0020

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title = "Management of Immunotherapy-Related Toxicities, Version 1.2022, NCCN Clinical Practice Guidelines in Oncology",

abstract = "The aim of the NCCN Guidelines for Management of Immunotherapy-Related Toxicities is to provide guidance on the management of immune-related adverse events resulting from cancer immunotherapy. The NCCN Management of Immunotherapy-Related Toxicities Panel is an interdisciplinary group of representatives from NCCN Member Institutions, consisting of medical and hematologic oncologists with expertise across a wide range of disease sites, and experts from the areas of dermatology, gastroenterology, endocrinology, neurooncology, nephrology, cardio-oncology, ophthalmology, pulmonary medicine, and oncology nursing. The content featured in this issue is an excerpt of the recommendations for managing toxicities related to CAR T-cell therapies and a review of existing evidence. For the full version of the NCCN Guidelines, including recommendations for managing toxicities related to immune checkpoint inhibitors, visit NCCN.org.",

keywords = "Humans, Immune Checkpoint Inhibitors, Immunologic Factors/therapeutic use, Immunotherapy/adverse effects, Medical Oncology, Neoplasms/drug therapy",

author = "Thompson, \{John A.\} and Schneider, \{Bryan J.\} and Julie Brahmer and Amaka Achufusi and Philippe Armand and Berkenstock, \{Meghan K.\} and Shailender Bhatia and Budde, \{Lihua E.\} and Saurin Chokshi and Marianne Davies and Amro Elshoury and Yaron Gesthalter and Aparna Hegde and Michael Jain and Kaffenberger, \{Benjamin H.\} and Lechner, \{Melissa G.\} and Tianhong Li and Alissa Marr and Suzanne McGettigan and Jordan McPherson and Theresa Medina and Mohindra, \{Nisha A.\} and Olszanski, \{Anthony J.\} and Olalekan Oluwole and Patel, \{Sandip P.\} and Pradnya Patil and Sunil Reddy and Mabel Ryder and Bianca Santomasso and Scott Shofer and Sosman, \{Jeffrey A.\} and Yinghong Wang and Zaha, \{Vlad G.\} and Megan Lyons and Mary Dwyer and Lisa Hang",

year = "2022",

month = apr,

doi = "10.6004/jnccn.2022.0020",

language = "English",

volume = "20",

pages = "387--405",

journal = "Journal of the National Comprehensive Cancer Network : JNCCN",

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Thompson, JA, Schneider, BJ, Brahmer, J, Achufusi, A, Armand, P, Berkenstock, MK, Bhatia, S, Budde, LE, Chokshi, S, Davies, M, Elshoury, A, Gesthalter, Y, Hegde, A, Jain, M, Kaffenberger, BH, Lechner, MG, Li, T, Marr, A, McGettigan, S, McPherson, J, Medina, T, Mohindra, NA, Olszanski, AJ, Oluwole, O, Patel, SP, Patil, P, Reddy, S, Ryder, M, Santomasso, B, Shofer, S, Sosman, JA, Wang, Y, Zaha, VG, Lyons, M, Dwyer, M & Hang, L 2022, 'Management of Immunotherapy-Related Toxicities, Version 1.2022, NCCN Clinical Practice Guidelines in Oncology', Journal of the National Comprehensive Cancer Network : JNCCN, vol. 20, no. 4, pp. 387-405. https://doi.org/10.6004/jnccn.2022.0020

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AU - Achufusi, Amaka

AU - Armand, Philippe

AU - Berkenstock, Meghan K.

AU - Bhatia, Shailender

AU - Budde, Lihua E.

AU - Chokshi, Saurin

AU - Davies, Marianne

AU - Elshoury, Amro

AU - Gesthalter, Yaron

AU - Hegde, Aparna

AU - Jain, Michael

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AU - Lechner, Melissa G.

AU - Li, Tianhong

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AU - McGettigan, Suzanne

AU - McPherson, Jordan

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AU - Mohindra, Nisha A.

AU - Olszanski, Anthony J.

AU - Oluwole, Olalekan

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AU - Patil, Pradnya

AU - Reddy, Sunil

AU - Ryder, Mabel

AU - Santomasso, Bianca

AU - Shofer, Scott

AU - Sosman, Jeffrey A.

AU - Wang, Yinghong

AU - Zaha, Vlad G.

AU - Lyons, Megan

AU - Dwyer, Mary

AU - Hang, Lisa

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AB - The aim of the NCCN Guidelines for Management of Immunotherapy-Related Toxicities is to provide guidance on the management of immune-related adverse events resulting from cancer immunotherapy. The NCCN Management of Immunotherapy-Related Toxicities Panel is an interdisciplinary group of representatives from NCCN Member Institutions, consisting of medical and hematologic oncologists with expertise across a wide range of disease sites, and experts from the areas of dermatology, gastroenterology, endocrinology, neurooncology, nephrology, cardio-oncology, ophthalmology, pulmonary medicine, and oncology nursing. The content featured in this issue is an excerpt of the recommendations for managing toxicities related to CAR T-cell therapies and a review of existing evidence. For the full version of the NCCN Guidelines, including recommendations for managing toxicities related to immune checkpoint inhibitors, visit NCCN.org.

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ER -

Management of Immunotherapy-Related Toxicities, Version 1.2022, NCCN Clinical Practice Guidelines in Oncology

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Keywords

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