Lung cancer in women: Emerging differences in epidemiology, biology, and therapy

Leno Thomas, L. Austin Doyle, Martin J. Edelman

Research output: Contribution to journalReview articlepeer-review

163 Scopus citations

Abstract

Lung cancer is the major cause of cancer-related death in both men and women in the United States. Emerging evidence indicates that there are differences in the pathogenesis and possibly increased susceptibility to lung cancer in women. In addition, considerable data support small, but important differences favoring women in terms of response to therapy and long-term survival after the diagnosis of lung cancer, regardless of histology or stage. These differences in both biology and outcome will be important considerations in the design of future trials of screening and therapy for lung cancer.

Original languageEnglish
Pages (from-to)370-381
Number of pages12
JournalChest
Volume128
Issue number1
DOIs
StatePublished - Jul 2005
Externally publishedYes

Keywords

  • DNA repair
  • Estrogen receptor
  • Human papilloma virus
  • Non-small cell lung cancer
  • Sex
  • Small cell lung cancer

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