LACK OF COMMON HAPLOTYPE AMONG FOUR FAMILY MEMBERS WITH LATE‐ONSET KAPOSI'S SARCOMA

J. R. Neefe; J. A. Treat; B. K. Chun; P. S. Schein; A. H. Johnson

doi:10.1111/j.1744-313X.1989.tb00467.x

LACK OF COMMON HAPLOTYPE AMONG FOUR FAMILY MEMBERS WITH LATE‐ONSET KAPOSI'S SARCOMA

J. R. Neefe, J. A. Treat, B. K. Chun, P. S. Schein, A. H. Johnson

University of Kentucky

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Abstract

Kaposi's sarcoma is associated with an increased frequency of HLA‐DR5. The hypothesized model of a susceptibility gene in linkage disequilibrium with DR5 may be tested by haplotype analysis in familial Kaposi's sarcoma. Our finding of no common haplotype among afflicted members of a family provides evidence against the hypothesized linkage.

Original language	English
Pages (from-to)	247-250
Number of pages	4
Journal	International Journal of Immunogenetics
Volume	16
Issue number	3
DOIs	https://doi.org/10.1111/j.1744-313X.1989.tb00467.x
State	Published - Jun 1989

Keywords

Aged
Aged, 80 and over
Disease Susceptibility
Female
HLA-DR5 Antigen/genetics
Haplotypes
Histocompatibility Testing
Humans
Male
Pedigree
Sarcoma, Kaposi/genetics

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10.1111/j.1744-313X.1989.tb00467.x

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title = "LACK OF COMMON HAPLOTYPE AMONG FOUR FAMILY MEMBERS WITH LATE‐ONSET KAPOSI'S SARCOMA",

abstract = "Kaposi's sarcoma is associated with an increased frequency of HLA‐DR5. The hypothesized model of a susceptibility gene in linkage disequilibrium with DR5 may be tested by haplotype analysis in familial Kaposi's sarcoma. Our finding of no common haplotype among afflicted members of a family provides evidence against the hypothesized linkage.",

keywords = "Aged, Aged, 80 and over, Disease Susceptibility, Female, HLA-DR5 Antigen/genetics, Haplotypes, Histocompatibility Testing, Humans, Male, Pedigree, Sarcoma, Kaposi/genetics",

author = "Neefe, {J. R.} and Treat, {J. A.} and Chun, {B. K.} and Schein, {P. S.} and Johnson, {A. H.}",

year = "1989",

month = jun,

doi = "10.1111/j.1744-313X.1989.tb00467.x",

language = "English",

volume = "16",

pages = "247--250",

journal = "International Journal of Immunogenetics",

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T1 - LACK OF COMMON HAPLOTYPE AMONG FOUR FAMILY MEMBERS WITH LATE‐ONSET KAPOSI'S SARCOMA

AU - Neefe, J. R.

AU - Treat, J. A.

AU - Chun, B. K.

AU - Schein, P. S.

AU - Johnson, A. H.

PY - 1989/6

Y1 - 1989/6

N2 - Kaposi's sarcoma is associated with an increased frequency of HLA‐DR5. The hypothesized model of a susceptibility gene in linkage disequilibrium with DR5 may be tested by haplotype analysis in familial Kaposi's sarcoma. Our finding of no common haplotype among afflicted members of a family provides evidence against the hypothesized linkage.

AB - Kaposi's sarcoma is associated with an increased frequency of HLA‐DR5. The hypothesized model of a susceptibility gene in linkage disequilibrium with DR5 may be tested by haplotype analysis in familial Kaposi's sarcoma. Our finding of no common haplotype among afflicted members of a family provides evidence against the hypothesized linkage.

KW - Aged

KW - Aged, 80 and over

KW - Disease Susceptibility

KW - Female

KW - HLA-DR5 Antigen/genetics

KW - Haplotypes

KW - Histocompatibility Testing

KW - Humans

KW - Male

KW - Pedigree

KW - Sarcoma, Kaposi/genetics

UR - http://www.scopus.com/inward/record.url?scp=0024819712&partnerID=8YFLogxK

U2 - 10.1111/j.1744-313X.1989.tb00467.x

DO - 10.1111/j.1744-313X.1989.tb00467.x

M3 - Article

C2 - 2614074

AN - SCOPUS:0024819712

SN - 1744-3121

VL - 16

SP - 247

EP - 250

JO - International Journal of Immunogenetics

JF - International Journal of Immunogenetics

IS - 3

ER -

LACK OF COMMON HAPLOTYPE AMONG FOUR FAMILY MEMBERS WITH LATE‐ONSET KAPOSI'S SARCOMA

Abstract

Keywords

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