TY - JOUR
T1 - Knowledge, attitudes, and self-efficacy as predictors of preparedness for oncology clinical trials
T2 - A mediational model
AU - Manne, Sharon
AU - Kashy, Deborah
AU - Albrecht, Terrance
AU - Wong, Yu Ning
AU - Flamm, Anne Lederman
AU - Benson, Al B.
AU - Miller, Suzanne M.
AU - Fleisher, Linda
AU - Buzaglo, Joanne
AU - Roach, Nancy
AU - Katz, Michael
AU - Ross, Eric
AU - Collins, Michael
AU - Poole, David
AU - Raivitch, Stephanie
AU - Miller, Dawn M.
AU - Kinzy, Tyler G.
AU - Liu, Tasnuva
AU - Meropol, Neal J.
PY - 2014/5
Y1 - 2014/5
N2 - Objective. This study used the Ottawa Decision Support Framework to evaluate a model examining associations between clinical trial knowledge, attitudinal barriers to participating in clinical trials, clinical trial self-efficacy, and clinical trial preparedness among 1256 cancer patients seen for their first outpatient consultation at a cancer center. As an exploratory aim, moderator effects for gender, race/ethnicity, education, and metastatic status on associations in the model were evaluated. Methods. Patients completed measures of cancer clinical trial knowledge, attitudinal barriers, self-efficacy, and preparedness. Structural equation modeling (SEM) was conducted to evaluate whether self-efficacy mediated the association between knowledge and barriers with preparedness. Results. The SEM explained 26% of the variance in cancer clinical trial preparedness. Self-efficacy mediated the associations between attitudinal barriers and preparedness, but self-efficacy did not mediate the knowledge-preparedness relationship. Conclusions. Findings partially support the Ottawa Decision Support Framework and suggest that assessing patients' level of self-efficacy may be just as important as evaluating their knowledge and attitudes about cancer clinical trials.
AB - Objective. This study used the Ottawa Decision Support Framework to evaluate a model examining associations between clinical trial knowledge, attitudinal barriers to participating in clinical trials, clinical trial self-efficacy, and clinical trial preparedness among 1256 cancer patients seen for their first outpatient consultation at a cancer center. As an exploratory aim, moderator effects for gender, race/ethnicity, education, and metastatic status on associations in the model were evaluated. Methods. Patients completed measures of cancer clinical trial knowledge, attitudinal barriers, self-efficacy, and preparedness. Structural equation modeling (SEM) was conducted to evaluate whether self-efficacy mediated the association between knowledge and barriers with preparedness. Results. The SEM explained 26% of the variance in cancer clinical trial preparedness. Self-efficacy mediated the associations between attitudinal barriers and preparedness, but self-efficacy did not mediate the knowledge-preparedness relationship. Conclusions. Findings partially support the Ottawa Decision Support Framework and suggest that assessing patients' level of self-efficacy may be just as important as evaluating their knowledge and attitudes about cancer clinical trials.
KW - Ottawa Decision Support Framework
KW - cancer clinical trials
KW - cancer patients
UR - http://www.scopus.com/inward/record.url?scp=84899551450&partnerID=8YFLogxK
UR - https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=purepublist2023&SrcAuth=WosAPI&KeyUT=WOS:000334398900007&DestLinkType=FullRecord&DestApp=WOS
U2 - 10.1177/0272989X13511704
DO - 10.1177/0272989X13511704
M3 - Article
C2 - 24246567
SN - 0272-989X
VL - 34
SP - 454
EP - 463
JO - Medical Decision Making
JF - Medical Decision Making
IS - 4
ER -
