TY - JOUR
T1 - Is There Any Benefit to the Use of Antibiotics with Indwelling Catheters after Urologic Surgery in Adults
AU - Maffucci, Fenizia
AU - Chang, Chrystal
AU - Simhan, Jay
AU - Cohn, Joshua A.
N1 - Publisher Copyright:
© 2023 by the authors.
PY - 2023/1
Y1 - 2023/1
N2 - Antibiotic stewardship in urologic reconstruction is critically important, as many patients will require indwelling catheters for days to weeks following surgery and thus are at risk of both developing catheter-associated urinary tract infections (CAUTI) as well as multi-drug resistant (MDR) uropathogens. Accordingly, limiting antibiotic use, when safe, should help reduce antibiotic resistance and the prevalence of MDR organisms. However, there is significant heterogeneity in how antibiotics are prescribed to patients who need indwelling urethral catheters post-operatively. We performed a literature review to determine if there are benefits in the use of antibiotics for various clinical scenarios that require post-operative indwelling catheters for greater than 24 h. In general, for patients undergoing prostatectomy, transurethral resection of the prostate, and/or urethroplasty, antibiotic administration may be limited without increased risk of CAUTI. However, more work is needed to identify optimal antibiotic regimens for these and alternative urologic procedures, whether certain sub-populations benefit from longer courses of antibiotics, and effective non-antibiotic or non-systemic therapies.
AB - Antibiotic stewardship in urologic reconstruction is critically important, as many patients will require indwelling catheters for days to weeks following surgery and thus are at risk of both developing catheter-associated urinary tract infections (CAUTI) as well as multi-drug resistant (MDR) uropathogens. Accordingly, limiting antibiotic use, when safe, should help reduce antibiotic resistance and the prevalence of MDR organisms. However, there is significant heterogeneity in how antibiotics are prescribed to patients who need indwelling urethral catheters post-operatively. We performed a literature review to determine if there are benefits in the use of antibiotics for various clinical scenarios that require post-operative indwelling catheters for greater than 24 h. In general, for patients undergoing prostatectomy, transurethral resection of the prostate, and/or urethroplasty, antibiotic administration may be limited without increased risk of CAUTI. However, more work is needed to identify optimal antibiotic regimens for these and alternative urologic procedures, whether certain sub-populations benefit from longer courses of antibiotics, and effective non-antibiotic or non-systemic therapies.
KW - antibiotic prophylaxis
KW - catheter-related infections
KW - prostatectomy
KW - transurethral resection of prostate
KW - urethral diseases
KW - urinary catheter
KW - urinary tract infection
KW - urology
UR - http://www.scopus.com/inward/record.url?scp=85146712119&partnerID=8YFLogxK
U2 - 10.3390/antibiotics12010156
DO - 10.3390/antibiotics12010156
M3 - Review article
C2 - 36671357
AN - SCOPUS:85146712119
SN - 2079-6382
VL - 12
JO - Antibiotics
JF - Antibiotics
IS - 1
M1 - 156
ER -